| Descriptor English: | Wiskott-Aldrich Syndrome Protein Family | ||||||
| Descriptor Spanish: |
Familia de Proteínas del Síndrome de Wiskott-Aldrich
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| Descriptor Portuguese: | Família de Proteínas da Síndrome de Wiskott-Aldrich | ||||||
| Descriptor French: | Famille de protéines du syndrome de Wiskott-Aldrich | ||||||
| Entry term(s): |
WAS Protein Family WAS Protein Family, Member 1 WAS Protein Family, Member 2 WAS Protein Family, Member 3 WASF1 Protein WASF2 Protein WASF3 Protein WASP Family Verprolin Homologous Proteins WASP Protein Family WASP-Family Verprolin Homologous Proteins WAVE Proteins WAVE1 Protein WAVE2 Protein WAVE3 Protein Wiskott Aldrich Syndrome Protein Family Wiskott Aldrich Syndrome Protein Family, Member 1 Wiskott Aldrich Syndrome Protein Family, Member 2 Wiskott Aldrich Syndrome Protein Family, Member 3 Wiskott-Aldrich Syndrome Protein Family, Member 1 Wiskott-Aldrich Syndrome Protein Family, Member 2 Wiskott-Aldrich Syndrome Protein Family, Member 3 |
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| Tree number(s): |
D05.750.078.730.912 D12.776.220.525.912 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D051300 | ||||||
| Scope note: | A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN. |
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| Annotation: | WISKOTT-ALDRICH SYNDROME PROTEIN and WISKOTT-ALDRICH SYNDROME PROTEIN, NEURONAL are also available |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2006; WAVE PROTEINS was indexed under MICROFILAMENT PROTEINS 1999-2005 |
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| History Note: | 2006(1999) |
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| DeCS ID: | 50563 | ||||||
| Unique ID: | D051300 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 | ||||||
| Revision Date: | 2013/07/09 |
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CHEMICALS AND DRUGS
Macromolecular Substances [D05]Macromolecular Substances -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Wiskott-Aldrich Syndrome Protein Family
- Preferred
Wiskott-Aldrich Syndrome Protein Family, Member 3
- Narrower
Wiskott-Aldrich Syndrome Protein Family, Member 2
- Narrower
WASP-Family Verprolin Homologous Proteins
- Narrower
Wiskott-Aldrich Syndrome Protein Family, Member 1
- Narrower
| Concept UI |
M0480078 |
| Scope note | A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN. |
| Preferred term | Wiskott-Aldrich Syndrome Protein Family |
| Entry term(s) |
WAS Protein Family WASP Protein Family Wiskott Aldrich Syndrome Protein Family |
| Concept UI |
M0480130 |
| Preferred term | Wiskott-Aldrich Syndrome Protein Family, Member 3 |
| Entry term(s) |
WAS Protein Family, Member 3 WASF3 Protein WAVE3 Protein Wiskott Aldrich Syndrome Protein Family, Member 3 |
| Concept UI |
M0480129 |
| Preferred term | Wiskott-Aldrich Syndrome Protein Family, Member 2 |
| Entry term(s) |
WAS Protein Family, Member 2 WASF2 Protein WAVE2 Protein Wiskott Aldrich Syndrome Protein Family, Member 2 |
| Concept UI |
M0481814 |
| Preferred term | WASP-Family Verprolin Homologous Proteins |
| Entry term(s) |
WASP Family Verprolin Homologous Proteins WAVE Proteins |
| Concept UI |
M0301786 |
| Preferred term | Wiskott-Aldrich Syndrome Protein Family, Member 1 |
| Entry term(s) |
WAS Protein Family, Member 1 WASF1 Protein WAVE1 Protein Wiskott Aldrich Syndrome Protein Family, Member 1 |
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