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Descriptor English: Cortactin
Descriptor Spanish: Cortactina
Descriptor Portuguese: Cortactina
Descriptor French: Cortactine
Tree number(s): D05.750.078.730.281
D12.644.360.024.280
D12.776.157.057.014
D12.776.220.525.281
D12.776.476.024.311
D12.776.744.390
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051356
Scope note: A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organization. It is also an SH3 DOMAIN containing phosphoprotein, and it mediates tyrosine PHOSPHORYLATION based SIGNAL TRANSDUCTION by PROTO-ONCOGENE PROTEIN PP60(C-SRC).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; CORTACTIN was indexed under MICROFILAMENT PROTEINS 1993-2005
History Note: 2006(1983)
DeCS ID: 50561
Unique ID: D051356
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/11/23
Cortactin - Preferred
Concept UI M0214241
Scope note A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organization. It is also an SH3 DOMAIN containing phosphoprotein, and it mediates tyrosine PHOSPHORYLATION based SIGNAL TRANSDUCTION by PROTO-ONCOGENE PROTEIN PP60(C-SRC).
Preferred term Cortactin



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