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Descriptor English: Actin Depolymerizing Factors
Descriptor Spanish: Factores Despolimerizantes de la Actina
Descriptor factores despolimerizantes de la actina
Entry term(s) cofilina
cofilinas
proteína despolimerizante de actina
Scope note: Familia de proteínas de bajo PESO MOLECULAR que se unen a la actina y se encuentran en los eucariotas. Remodelan el CITOESQUELETO de actina escindiendo los FILAMENTOS DE ACTINA y aumentando la velocidad de disociación de monómeros.
Descriptor Portuguese: Fatores de Despolimerização de Actina
Descriptor French: Facteurs de dépolymérisation de l'actine
Entry term(s): ADF Proteins (Actin Depolymerizing Factors)
Actin Depolymerizing Protein
Actin Depolymerizing Proteins
Cofilin
Cofilin Proteins
Cofilins
Depolymerizing Factors, Actin
Depolymerizing Protein, Actin
Depolymerizing Proteins, Actin
Protein, Actin Depolymerizing
Tree number(s): D05.750.078.730.212
D12.776.220.525.212
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051339
Scope note: A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; ACTIN DEPOLYMERIZING FACTORS was indexed under MICROFILAMENT PROTEINS 1988-2005, & under MUSCLE PROTEINS & PROTEINS 1981-1987
History Note: 2006(1981)
DeCS ID: 50554
Unique ID: D051339
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2020/05/27
Actin Depolymerizing Factors - Preferred
Concept UI M0128858
Scope note A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.
Preferred term Actin Depolymerizing Factors
Entry term(s) ADF Proteins (Actin Depolymerizing Factors)
Actin Depolymerizing Protein
Actin Depolymerizing Proteins
Cofilin
Cofilin Proteins
Cofilins
Depolymerizing Factors, Actin
Depolymerizing Protein, Actin
Depolymerizing Proteins, Actin
Protein, Actin Depolymerizing



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