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Descriptor English: 3-Isopropylmalate Dehydrogenase
Descriptor Spanish: 3-Isopropilmalato Deshidrogenasa
Descriptor 3-isopropilmalato deshidrogenasa
Scope note: Enzima dependiente de NAD+ que cataliza la oxidación de 3-carboxi-2-hidroxi-4-metilpentanoato a 3-carboxi-4-metil-2-oxopentanoato. Está implicada en la biosíntesis de la VALINA, LEUCINA e ISOLEUCINA.
Descriptor Portuguese: 3-Isopropilmalato Desidrogenase
Descriptor French: 3-Isopropylmalate dehydrogenase
Entry term(s): 3 Isopropylmalate Dehydrogenase
Dehydrogenase, 3-Isopropylmalate
Dehydrogenase, beta-IPM
Dehydrogenase, beta-Isopropylmalate
beta IPM Dehydrogenase
beta Isopropylmalate Dehydrogenase
beta-IPM Dehydrogenase
beta-Isopropylmalate Dehydrogenase
Tree number(s): D08.811.682.047.820.193
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050539
Scope note: An NAD+ dependent enzyme that catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate to 3-carboxy-4-methyl-2-oxopentanoate. It is involved in the biosynthesis of VALINE; LEUCINE; and ISOLEUCINE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.1.1.85
Public MeSH Note: 2006; 3-ISOPROPYLMALATE DEHYDROGENASE was indexed under ALCOHOL OXIDOREDUCTASES 1981-2005, & under DICARBOXYLIC ACIDS 1970-1980
History Note: 2006(1980); use DICARBOXYLIC ACIDS 1970-1979
DeCS ID: 50598
Unique ID: D050539
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2013/07/08
3-Isopropylmalate Dehydrogenase - Preferred
Concept UI M0076384
Scope note An NAD+ dependent enzyme that catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate to 3-carboxy-4-methyl-2-oxopentanoate. It is involved in the biosynthesis of VALINE; LEUCINE; and ISOLEUCINE.
Preferred term 3-Isopropylmalate Dehydrogenase
Entry term(s) 3 Isopropylmalate Dehydrogenase
Dehydrogenase, 3-Isopropylmalate
Dehydrogenase, beta-IPM
Dehydrogenase, beta-Isopropylmalate
beta IPM Dehydrogenase
beta Isopropylmalate Dehydrogenase
beta-IPM Dehydrogenase
beta-Isopropylmalate Dehydrogenase



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