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Descriptor English: Indoleamine-Pyrrole 2,3,-Dioxygenase
Descriptor Spanish: Indolamina-Pirrol 2,3,-Dioxigenasa
Descriptor indolamina-pirrol 2,3,-dioxigenasa
Scope note: Dioxigenasa con especificidad para la oxidación del anillo indolamina del TRIPTÓFANO. Es una enzima extrahepática que interviene en el metabolismo como enzima primera y limitante de la velocidad en la vía de la quinurenina del catabolismo del TRIPTÓFANO.
Descriptor Portuguese: Indolamina-Pirrol 2,3,-Dioxigenase
Descriptor French: Indoleamine-pyrrole 2,3,-dioxygenase
Entry term(s): Dioxygenase, IDO
IDO Dioxygenase
Indolamine 2,3 Dioxygenase
Indolamine-2,3-Dioxygenase
Indoleamine 2,3 Dioxygenase
Indoleamine 2,3-Dioxygenase
Indoleamine-Oxygen 2,3-Oxidoreductase (Decyclizing)
Tree number(s): D08.811.682.690.416.333
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050503
Scope note: A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is an extrahepatic enzyme that plays a role in metabolism as the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Dioxygenases (2005)
Oxygenases (1970-2004)
Tryptophan Oxygenase (1968-2005)
Public MeSH Note: 2006; see TRYPTOPHAN OXYGENASE 1990-2005; INDOLAMINE-2,3-DIOXYGENASE was indexed under DIOXYGENASES 2005 and OXYGENASES 1990-2004
History Note: 2006(1990)
DeCS ID: 50656
Unique ID: D050503
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2012/07/03
Indoleamine-Pyrrole 2,3,-Dioxygenase - Preferred
Concept UI M0475654
Scope note A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is an extrahepatic enzyme that plays a role in metabolism as the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.
Preferred term Indoleamine-Pyrrole 2,3,-Dioxygenase
Entry term(s) Dioxygenase, IDO
IDO Dioxygenase
Indolamine 2,3 Dioxygenase
Indolamine-2,3-Dioxygenase
Indoleamine 2,3 Dioxygenase
Indoleamine 2,3-Dioxygenase
Indoleamine-Oxygen 2,3-Oxidoreductase (Decyclizing)



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