| Descriptor English: | Tryptophan Oxygenase | ||||||
| Descriptor Spanish: |
Triptófano Oxigenasa
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| Descriptor Portuguese: | Triptofano Oxigenase | ||||||
| Descriptor French: | Tryptophane 2,3-dioxygenase | ||||||
| Entry term(s): |
2,3-Dioxygenase, Tryptophan Dioxygenase, TDO Oxygenase, Tryptophan Pyrrolase, Tryptophan TDO Dioxygenase Tryptophan 2,3 Dioxygenase Tryptophan 2,3-Dioxygenase Tryptophan Pyrrolase |
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| Tree number(s): |
D08.811.682.690.416.722 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D014366 | ||||||
| Scope note: | A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is a LIVER-specific enzyme that is the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 1.13.11.11 | ||||||
| CAS Type 1 Name: | L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing) | ||||||
| Public MeSH Note: | 68 |
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| History Note: | 68(65) |
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| Related: |
Tryptophan Hydroxylase
MeSH | ||||||
| DeCS ID: | 14768 | ||||||
| Unique ID: | D014366 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1968/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2005/06/30 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Tryptophan Oxygenase
- Preferred
| Concept UI |
M0022091 |
| Scope note | A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is a LIVER-specific enzyme that is the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism. |
| Preferred term | Tryptophan Oxygenase |
| Entry term(s) |
2,3-Dioxygenase, Tryptophan Dioxygenase, TDO Oxygenase, Tryptophan Pyrrolase, Tryptophan TDO Dioxygenase Tryptophan 2,3 Dioxygenase Tryptophan 2,3-Dioxygenase Tryptophan Pyrrolase |
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