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Descriptor English: Kynurenine 3-Monooxygenase
Descriptor Spanish: Quinurenina 3-Monooxigenasa
Descriptor quinurenina 3-monooxigenasa
Scope note: Flavina monooxigenasa dependiente del NADPH que desempeña un papel clave en el catabolismo del TRIPTÓFANO al catalizar la HIDROXILACIÓN de la QUINURENINA a 3-hidroxiquinurenina. Fue caracterizada previamente como EC 1.14.1.2 y EC 1.99.1.5.
Descriptor Portuguese: Quinurenina 3-Mono-Oxigenase
Descriptor French: Kynurenine 3-monooxygenase
Entry term(s): 3-Hydroxylase, Kynurenine
3-Monooxygenase, Kynurenine
Hydroxylase, Kynurenine
Kynurenine 3 Hydroxylase
Kynurenine 3 Monooxygenase
Kynurenine 3-Hydroxylase
Kynurenine Hydroxylase
L Kynurenine 3 Hydroxylase
L-Kynurenine-3-Hydroxylase
Tree number(s): D08.811.682.690.708.557
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050601
Scope note: An NADPH-dependent flavin monooxygenase that plays a key role in the catabolism of TRYPTOPHAN by catalyzing the HYDROXYLATION of KYNURENINE to 3-hydroxykynurenine. It was formerly characterized as EC 1.14.1.2 and EC 1.99.1.5.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.14.13.9
Public MeSH Note: 2006; KYNURENINE 3-MONOOXYGENASE was indexed under MIXED FUNCTION OXYGENASES 1981-2005, & under KYNURENINE 1973-1980
History Note: 2006(1980); KYNURENINE 1973-1979
DeCS ID: 50663
Unique ID: D050601
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2013/07/09
Kynurenine 3-Monooxygenase - Preferred
Concept UI M0076440
Scope note An NADPH-dependent flavin monooxygenase that plays a key role in the catabolism of TRYPTOPHAN by catalyzing the HYDROXYLATION of KYNURENINE to 3-hydroxykynurenine. It was formerly characterized as EC 1.14.1.2 and EC 1.99.1.5.
Preferred term Kynurenine 3-Monooxygenase
Entry term(s) 3-Hydroxylase, Kynurenine
3-Monooxygenase, Kynurenine
Hydroxylase, Kynurenine
Kynurenine 3 Hydroxylase
Kynurenine 3 Monooxygenase
Kynurenine 3-Hydroxylase
Kynurenine Hydroxylase
L Kynurenine 3 Hydroxylase
L-Kynurenine-3-Hydroxylase



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