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Descriptor in English: Tryptophan Hydroxylase
Descriptor in Spanish: Triptófano Hidroxilasa
Descriptor in Portuguese: Triptofano Hidroxilase
Descriptor in French: Tryptophane 5-monooxygenase
Entry term(s): Hydroxylase, Tryptophan
Monooxygenase, Tryptophan
Tryptophan Monooxygenase
Tree number(s): D08.811.682.690.708.870
Scope note: An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 78(73); was see under HYDROXYLASES 1975-77
See also the descriptors: Tryptophan Oxygenase MeSH
DeCS UI: 14767
Descriptor UI: D014365
Date Established: 1978/01/01
Date of Entry: 1999/01/01
Revision Date: 2004/07/07
Tryptophan Hydroxylase - Preferred
Concept UI M0022090
Scope note An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN.
Preferred term Tryptophan Hydroxylase
Entry term(s) Hydroxylase, Tryptophan
Monooxygenase, Tryptophan
Tryptophan Monooxygenase



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