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Descriptor English: Tryptophan Hydroxylase
Descriptor Spanish: Triptófano Hidroxilasa
Descriptor triptófano hidroxilasa
Entry term(s) triptófano monooxigenasa
Scope note: Enzima qque cataliza la hidroxilación del TRIPTÓFANO a 5-HIDROXITRIPTÓFANO en presencia de NADPH y oxígeno molecular. Es importante en la biosíntesis de SEROTONINA.
Descriptor Portuguese: Triptofano Hidroxilase
Descriptor French: Tryptophane 5-monooxygenase
Entry term(s): Hydroxylase, Tryptophan
Monooxygenase, Tryptophan
Tryptophan Monooxygenase
Tree number(s): D08.811.682.690.708.870
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D014365
Scope note: An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.14.16.4
CAS Type 1 Name: L-tryptophan,tetrahydropteridine:oxygen oxidoreductase (5-hydroxylating)
Previous Indexing: Hydroxylases (1966-1972)
Public MeSH Note: 78; was see under HYDROXYLASES 1975-77
History Note: 78(73); was see under HYDROXYLASES 1975-77
Related: Tryptophan Oxygenase MeSH
DeCS ID: 14767
Unique ID: D014365
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1978/01/01
Date of Entry: 1999/01/01
Revision Date: 2004/07/07
Tryptophan Hydroxylase - Preferred
Concept UI M0022090
Scope note An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN.
Preferred term Tryptophan Hydroxylase
Entry term(s) Hydroxylase, Tryptophan
Monooxygenase, Tryptophan
Tryptophan Monooxygenase



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