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Descriptor in English: Phenylalanine Hydroxylase
Descriptor in Spanish: Fenilalanina Hidroxilasa
Descriptor in Portuguese: Fenilalanina Hidroxilase
Descriptor in French: Phenylalanine 4-monooxygenase
Entry term(s): 4-Hydroxylase, Phenylalanine
4-Monooxygenase, Phenylalanine
Hydroxylase, Phenylalanine
Phenylalanine 4 Hydroxylase
Phenylalanine 4 Monooxygenase
Phenylalanine 4-Hydroxylase
Phenylalanine 4-Monooxygenase
Tree number(s): D08.811.682.690.708.601
Scope note: An enzyme of the oxidoreductase class that catalyzes the formation of L-TYROSINE, dihydrobiopterin, and water from L-PHENYLALANINE, tetrahydrobiopterin, and oxygen. Deficiency of this enzyme may cause PHENYLKETONURIAS and PHENYLKETONURIA, MATERNAL. EC 1.14.16.1.
Annotation: /defic: consider also PHENYLKETONURIAS and PHENYLKETONURIA, MATERNAL
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 73(71)
See also the descriptors: Phenylketonuria, Maternal MeSH
Phenylketonurias MeSH
DeCS UI: 10844
Descriptor UI: D010651
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2004/07/07
Phenylalanine Hydroxylase - Preferred
Concept UI M0016546
Scope note An enzyme of the oxidoreductase class that catalyzes the formation of L-TYROSINE, dihydrobiopterin, and water from L-PHENYLALANINE, tetrahydrobiopterin, and oxygen. Deficiency of this enzyme may cause PHENYLKETONURIAS and PHENYLKETONURIA, MATERNAL. EC 1.14.16.1.
Preferred term Phenylalanine Hydroxylase
Entry term(s) 4-Hydroxylase, Phenylalanine
4-Monooxygenase, Phenylalanine
Hydroxylase, Phenylalanine
Phenylalanine 4 Hydroxylase
Phenylalanine 4 Monooxygenase
Phenylalanine 4-Hydroxylase
Phenylalanine 4-Monooxygenase



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