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Descriptor English: Protein Kinase C-epsilon
Descriptor Spanish: Proteína Quinasa C-epsilon
Descriptor proteína cinasa C-epsilon
Entry term(s) proteincinasa C-epsilon
proteinquinasa C-epsilon
proteína quinasa C-epsilon
Scope note: Proteina cinasa del subtipo C caracterizada originalmente como serina-treonina cinasa independiente del CALCIO que es activada por ÉSTERES DE FORBOL y DIACILGLICEROLES. Está dirigida a compartimentos celulares específicos en respuesta a señales extracelulares que activan los RECEPTORES ACOPLADOS A LA PROTEÍNA G, los RECEPTORES DE TIROSINCINASA y proteína tirosina cinasas intracelulares.
Descriptor Portuguese: Proteína Quinase C-épsilon
Descriptor French: Protein kinase C-epsilon
Entry term(s): Kinase C-epsilon, Protein
PKC epsilon
PKC epsilon Serine Threonine Kinase
PKC-epsilon Serine Threonine Kinase
Protein Kinase C epsilon
Tree number(s): D08.811.913.696.620.682.700.725.750
D12.776.476.563.725.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051744
Scope note: A protein kinase C subtype that was originally characterized as a CALCIUM-independent, serine-threonine kinase that is activated by PHORBOL ESTERS and DIACYLGLYCEROLS. It is targeted to specific cellular compartments in response to extracellular signals that activate G-PROTEIN-COUPLED RECEPTORS; TYROSINE KINASE RECEPTORS; and intracellular protein tyrosine kinase.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.13
Public MeSH Note: 2006; PROTEIN KINASE C EPSILON was indexed under PROTEIN KINASE C 1994-2005
History Note: 2006(1994)
DeCS ID: 50723
Unique ID: D051744
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2009/07/06
Protein Kinase C-epsilon - Preferred
Concept UI M0234611
Scope note A protein kinase C subtype that was originally characterized as a CALCIUM-independent, serine-threonine kinase that is activated by PHORBOL ESTERS and DIACYLGLYCEROLS. It is targeted to specific cellular compartments in response to extracellular signals that activate G-PROTEIN-COUPLED RECEPTORS; TYROSINE KINASE RECEPTORS; and intracellular protein tyrosine kinase.
Preferred term Protein Kinase C-epsilon
Entry term(s) Kinase C-epsilon, Protein
PKC epsilon
PKC epsilon Serine Threonine Kinase
PKC-epsilon Serine Threonine Kinase
Protein Kinase C epsilon



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