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Descriptor English: Protein Kinase C beta
Descriptor Spanish: Proteína Quinasa C beta
Descriptor proteína cinasa C beta
Entry term(s) PKC beta
Scope note: PKC codifica dos proteínas (PKCB1 and PKCBII), generalmente por corte y empalme alternativo de los exones C-terminales. Está ampliamente distribuida y tiene un amplio rango de funciones en procesos como la regulación del receptor de células B, la apoptosis inducida por estrés oxidativo, la regulación transcripcional dependiente del receptor de andrógeno, la señalización insulínica y la proliferación de célula endoteliales.
Descriptor Portuguese: Proteína Quinase C beta
Descriptor French: Protein kinase C beta
Entry term(s): PKC beta 1
PKC beta 2
PKC beta II
PKC(beta)
PKC-beta II
PKCB1
PKCBII
PKCbeta2
Protein Kinase C beta I
Protein Kinase C beta II
Protein Kinase C beta1
Protein Kinase C beta2
Protein Kinase C-beta (II)
Protein Kinase C-beta(II)
beta 1, PKC
beta 2, PKC
Tree number(s): D08.811.913.696.620.682.700.725.049
D12.776.476.563.725.049
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064546
Scope note: PKC beta encodes two proteins (PKCB1 and PKCBII) generated by alternative splicing of C-terminal exons. It is widely distributed with wide-ranging roles in processes such as B-cell receptor regulation, oxidative stress-induced apoptosis, androgen receptor-dependent transcriptional regulation, insulin signaling, and endothelial cell proliferation.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.13
Public MeSH Note: 2014; was indexed under Isoenzymes 1999-2003 and Protein Kinase C 2003-2013
History Note: 2014
DeCS ID: 55306
Unique ID: D064546
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Revision Date: 2016/06/28
Protein Kinase C beta - Preferred
Concept UI M0234129
Scope note PKC beta encodes two proteins (PKCB1 and PKCBII) generated by alternative splicing of C-terminal exons. It is widely distributed with wide-ranging roles in processes such as B-cell receptor regulation, oxidative stress-induced apoptosis, androgen receptor-dependent transcriptional regulation, insulin signaling, and endothelial cell proliferation.
Preferred term Protein Kinase C beta
Entry term(s) PKC(beta)
Protein Kinase C beta2 - Narrower
Concept UI M0492418
Preferred term Protein Kinase C beta2
Entry term(s) PKC beta 2
PKC beta II
PKC-beta II
PKCBII
PKCbeta2
Protein Kinase C beta I
Protein Kinase C beta II
Protein Kinase C-beta (II)
Protein Kinase C-beta(II)
beta 2, PKC
Protein Kinase C beta1 - Narrower
Concept UI M0427950
Preferred term Protein Kinase C beta1
Entry term(s) PKC beta 1
PKCB1
beta 1, PKC



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