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Descriptor English: Interferon Regulatory Factors
Descriptor Spanish: Factores Reguladores del Interferón
Descriptor factores reguladores del interferón
Entry term(s) factor regulador del interferón
Scope note: Familia de factores de transcripción que comparten un MOTIVO HÉLICE-GIRO-HÉLICE N-terminal y se unen a PROMOTORES inducibles por el INTERFERÓN para controlar la expresión de GENES. Las proteínas IRF se unen a secuencias específicas de ADN tales como los elementos de respuesta estimulados por el interferón, los elementos reguladores del interferón y la secuencia de consenso de interferón.
Descriptor Portuguese: Fatores Reguladores de Interferon
Descriptor French: Facteurs de régulation d'interféron
Entry term(s): Factor, Interferon Regulatory
IRF Transcription Factors
Interferon Regulatory Factor
Regulatory Factor, Interferon
Transcription Factors, IRF
Tree number(s): D12.644.360.024.302
D12.776.157.057.050
D12.776.260.504
D12.776.476.024.385
D12.776.930.332
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050835
Scope note: A family of transcription factors that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to control GENE expression. IRF proteins bind specific DNA sequences such as interferon-stimulated response elements, interferon regulatory elements, and the interferon consensus sequence.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006
History Note: 2006
DeCS ID: 50774
Unique ID: D050835
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2020/05/27
Interferon Regulatory Factors - Preferred
Concept UI M0478209
Scope note A family of transcription factors that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to control GENE expression. IRF proteins bind specific DNA sequences such as interferon-stimulated response elements, interferon regulatory elements, and the interferon consensus sequence.
Preferred term Interferon Regulatory Factors
Entry term(s) Factor, Interferon Regulatory
IRF Transcription Factors
Interferon Regulatory Factor
Regulatory Factor, Interferon
Transcription Factors, IRF



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