| Descriptor English: | Interferon Regulatory Factor-3 | ||||||
| Descriptor Spanish: |
Factor 3 Regulador del Interferón
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| Descriptor Portuguese: | Fator Regulador 3 de Interferon | ||||||
| Descriptor French: | Facteur-3 de régulation d'interféron | ||||||
| Entry term(s): |
IFN Regulatory Factor 3 IFN-Regulatory Factor 3 IRF 3 Transcription Factor IRF-3 Transcription Factor Interferon Regulatory Factor 3 Transcription Factor, IRF-3 |
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| Tree number(s): |
D12.644.360.024.302.374 D12.776.157.057.050.374 D12.776.260.504.374 D12.776.476.024.385.374 D12.776.744.562 D12.776.930.332.374 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050838 | ||||||
| Scope note: | An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2006; INTERFERON REGULATORY FACTOR-3 was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1996-2005 |
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| History Note: | 2006(1996) |
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| DeCS ID: | 50777 | ||||||
| Unique ID: | D050838 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 | ||||||
| Revision Date: | 2015/11/23 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Interferon Regulatory Factor-3
- Preferred
| Concept UI |
M0255479 |
| Scope note | An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription. |
| Preferred term | Interferon Regulatory Factor-3 |
| Entry term(s) |
IFN Regulatory Factor 3 IFN-Regulatory Factor 3 IRF 3 Transcription Factor IRF-3 Transcription Factor Interferon Regulatory Factor 3 Transcription Factor, IRF-3 |
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