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Descriptor English: Cyclin-Dependent Kinase Inhibitor p18
Descriptor Spanish: Inhibidor p18 de las Quinasas Dependientes de la Ciclina
Descriptor inhibidor p18 de cinasas dependientes de ciclinas
Scope note: Inhibidor INK4 de las cinasas dependientes de la ciclina que contiene cinco REPETICIONES DE TIPO ANQUIRINA. La expresión aberrante de esta proteína se ha asociado a la alteración de la regulación del crecimiento de las CÉLULAS EPITELIALES, hipertrofia de órganos y diversas NEOPLASIAS.
Descriptor Portuguese: Inibidor de Quinase Dependente de Ciclina p18
Descriptor French: Inhibiteur p18 de kinase cycline-dépendante
Entry term(s): CDK6 Associated Protein p18
CDK6 Inhibitor, p18
CDK6-Associated Protein p18
CDKN2C Protein
Cyclin Dependent Kinase Inhibitor 2C
Cyclin Dependent Kinase Inhibitor p18
Cyclin-Dependent Kinase Inhibitor 2C
INK4C Protein
p18 CDK6 Inhibitor
p18, CDK6-Associated Protein
p18INK4c Protein
Tree number(s): D12.644.360.225.300
D12.776.167.187.300
D12.776.476.225.300
D12.776.624.776.355.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050763
Scope note: An INK4 cyclin-dependent kinase inhibitor containing five ANKYRIN-LIKE REPEATS. Aberrant expression of this protein has been associated with deregulated EPITHELIAL CELL growth, organ enlargement, and a variety of NEOPLASMS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Protein Kinase Inhibitors
Public MeSH Note: 2006; CYCLIN-DEPENDENT KINASE INHIBITOR P 18 was indexed under TUMOR SUPPRESSOR PROTEINS & CELL CYCLE PROTEINS 2002-2005, & under CARRIER PROTEINS 1994-2001
History Note: 2006(1994)
DeCS ID: 50929
Unique ID: D050763
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/11/23
Cyclin-Dependent Kinase Inhibitor p18 - Preferred
Concept UI M0240536
Scope note An INK4 cyclin-dependent kinase inhibitor containing five ANKYRIN-LIKE REPEATS. Aberrant expression of this protein has been associated with deregulated EPITHELIAL CELL growth, organ enlargement, and a variety of NEOPLASMS.
Preferred term Cyclin-Dependent Kinase Inhibitor p18
Entry term(s) CDK6 Associated Protein p18
CDK6 Inhibitor, p18
CDK6-Associated Protein p18
CDKN2C Protein
Cyclin Dependent Kinase Inhibitor 2C
Cyclin Dependent Kinase Inhibitor p18
Cyclin-Dependent Kinase Inhibitor 2C
INK4C Protein
p18 CDK6 Inhibitor
p18, CDK6-Associated Protein
p18INK4c Protein



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