| Descriptor English: | Cyclin-Dependent Kinase Inhibitor p21 | ||||
| Descriptor Spanish: |
Inhibidor p21 de las Quinasas Dependientes de la Ciclina
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| Descriptor Portuguese: | Inibidor de Quinase Dependente de Ciclina p21 | ||||
| Descriptor French: | Inhibiteur p21 de kinase cycline-dépendante | ||||
| Entry term(s): |
CDK2 Associated Protein 20 kDa CDK2-Associated Protein 20 kDa CDKN1 Protein CDKN1A Protein Cdk Interacting Protein 1 Cdk-Interacting Protein 1 Cdk2 Inhibitor Protein Cell Cycle Regulator p21 Cyclin Dependent Kinase Inhibitor 1A Protein Cyclin Dependent Kinase Inhibitor p21 Cyclin Kinase Inhibitor p21 Cyclin-Dependent Kinase Inhibitor 1A Protein Senescent Cell Derived Inhibitor Protein 1 Senescent Cell-Derived Inhibitor Protein 1 p21 Cell Cycle Regulator p21 Cyclin Kinase Inhibitor |
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| Tree number(s): |
D12.644.360.225.500 D12.776.157.687.250 D12.776.167.187.500 D12.776.476.225.500 D12.776.624.776.355.500 D12.776.660.720.250 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050759 | ||||
| Scope note: | A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN-DEPENDENT KINASES and associates with PROLIFERATING CELL NUCLEAR ANTIGEN and CASPASE 3. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Pharm Action: |
Protein Kinase Inhibitors |
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| Public MeSH Note: | 2006; CYCLIN-DEPENDENT KINASE INHIBITOR P21 was indexed under CYCLINS 1993-2005, & under CELL CYCLE PROTEINS 2005 |
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| History Note: | 2006(1993) |
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| DeCS ID: | 50931 | ||||
| Unique ID: | D050759 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 2006/01/01 | ||||
| Date of Entry: | 2005/06/30 | ||||
| Revision Date: | 2017/05/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Cyclin-Dependent Kinase Inhibitor p21
- Preferred
| Concept UI |
M0224308 |
| Scope note | A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN-DEPENDENT KINASES and associates with PROLIFERATING CELL NUCLEAR ANTIGEN and CASPASE 3. |
| Preferred term | Cyclin-Dependent Kinase Inhibitor p21 |
| Entry term(s) |
CDK2 Associated Protein 20 kDa CDK2-Associated Protein 20 kDa CDKN1 Protein CDKN1A Protein Cdk Interacting Protein 1 Cdk-Interacting Protein 1 Cdk2 Inhibitor Protein Cell Cycle Regulator p21 Cyclin Dependent Kinase Inhibitor 1A Protein Cyclin Dependent Kinase Inhibitor p21 Cyclin Kinase Inhibitor p21 Cyclin-Dependent Kinase Inhibitor 1A Protein Senescent Cell Derived Inhibitor Protein 1 Senescent Cell-Derived Inhibitor Protein 1 p21 Cell Cycle Regulator p21 Cyclin Kinase Inhibitor |
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