| Descriptor English: | Core Binding Factor Alpha 1 Subunit | ||||||
| Descriptor Spanish: |
Subunidad alfa 1 del Factor de Unión al Sitio Principal
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| Descriptor Portuguese: | Subunidade alfa 1 de Fator de Ligação ao Core | ||||||
| Descriptor French: | Sous-unité alpha 1 du facteur CBF | ||||||
| Entry term(s): |
AML3 Transcription Factor Acute Myeloid Leukemia 3 Protein CBFA 1 Protein CBFA-1 Protein CBFA1 Protein CBFalpha Runt Domain Transcription Factor 1 CBFalpha1 Protein Osf2 Transcription Factor PEBP2alphaA Protein Runx2 Protein SEF1 Protein SL3 3 Enhancer Factor 1 SL3-3 Enhancer Factor 1 |
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| Tree number(s): |
D12.776.930.155.200.100 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050659 | ||||||
| Scope note: | A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain and is involved in genetic regulation of skeletal development and CELL DIFFERENTIATION. |
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| Annotation: | see SCR for organism-specific terms |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Neoplasm Proteins (1997-2005) Transcription Factors (1997-2005) |
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| Public MeSH Note: | 2006; RUNX2 PROTEIN was indexed under NEOPLASM PROTEINS & TRANSCRIPTION FACTORS 1997-2005 |
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| History Note: | 2006(1997) |
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| DeCS ID: | 51176 | ||||||
| Unique ID: | D050659 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Core Binding Factor Alpha 1 Subunit
- Preferred
| Concept UI |
M0276678 |
| Scope note | A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain and is involved in genetic regulation of skeletal development and CELL DIFFERENTIATION. |
| Preferred term | Core Binding Factor Alpha 1 Subunit |
| Entry term(s) |
AML3 Transcription Factor Acute Myeloid Leukemia 3 Protein CBFA 1 Protein CBFA-1 Protein CBFA1 Protein CBFalpha Runt Domain Transcription Factor 1 CBFalpha1 Protein Osf2 Transcription Factor PEBP2alphaA Protein Runx2 Protein SEF1 Protein SL3 3 Enhancer Factor 1 SL3-3 Enhancer Factor 1 |
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