| Descriptor English: | Core Binding Factor Alpha 3 Subunit | ||||||
| Descriptor Spanish: |
Subunidad alfa 3 del Factor de Unión al Sitio Principal
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| Descriptor Portuguese: | Subunidade alfa 3 de Fator de Ligação ao Core | ||||||
| Descriptor French: | Sous-unité alpha 3 du facteur CBF | ||||||
| Entry term(s): |
AML2 Protein Acute Myeloid Leukemia 2 Protein CBFA3 Protein Core Binding Factor Alpha 3 Protein Core-Binding Factor Alpha 3 Protein PEBP2A3 Protein Runt Domain Transcription Factor AML-2 Runt Related Transcription Factor 3 Protein Runt-Related Transcription Factor 3 Protein Runx3 Protein |
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| Tree number(s): |
D12.776.930.155.200.300 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050677 | ||||||
| Scope note: | A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. |
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| Annotation: | see SCR for organism-specific terms |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
DNA-Binding Proteins (2001-2005) Transcription Factors (2001-2005) |
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| Public MeSH Note: | 2006; RUNX3 PROTEIN was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 2001-2005 |
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| History Note: | 2006(2001) |
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| DeCS ID: | 51178 | ||||||
| Unique ID: | D050677 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Core Binding Factor Alpha 3 Subunit
- Preferred
| Concept UI |
M0399600 |
| Scope note | A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. |
| Preferred term | Core Binding Factor Alpha 3 Subunit |
| Entry term(s) |
AML2 Protein Acute Myeloid Leukemia 2 Protein CBFA3 Protein Core Binding Factor Alpha 3 Protein Core-Binding Factor Alpha 3 Protein PEBP2A3 Protein Runt Domain Transcription Factor AML-2 Runt Related Transcription Factor 3 Protein Runt-Related Transcription Factor 3 Protein Runx3 Protein |
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