Search
Descriptor English: Cyclic Nucleotide Phosphodiesterases, Type 1
Descriptor Spanish: Fosfodiesterasas de Nucleótidos Cíclicos Tipo 1
Descriptor fosfodiesterasas de nucleótidos cíclicos de tipo 1
Entry term(s) fosfodiesterasas de nucleótidos cíclicos de tipo I
fosfodiesterasas de nucleótidos cíclicos del tipo I
fosfodiesterasas de nucleótidos cíclicos tipo 1
Scope note: Subfamilia de fosfodiesterasas de nucleótidos cíclicos dependientes del CALCIO y de la CALMODULINA. Los tres miembros de esta familia reciben la denominación de tipo 1A, tipo 1B y tipo 1C, y cada uno de ellos es producto de un gen distinto. Además, pueden producirse diversas variantes enzimáticas de cada subtipo debido a las múltiples alternativas de corte y empalme del ARNm. Aunque las enzimas de tipo 1 se clasifican como 3',5'-AMP cíclico fosfodiesterasas (EC 3.1.4.17), algunos miembros de esta clase tienen especificidad adicional por el GMP CÍCLICO.
Descriptor Portuguese: Nucleotídeo Cíclico Fosfodiesterase do Tipo 1
Descriptor French: Cyclic Nucleotide Phosphodiesterases, Type 1
Entry term(s): Ca CaM Phosphodiesterase
Ca(2+)-CaM-Stimulated PDE
Ca++ Calmodulin Dependent Cyclic AMP Phosphodiesterase
Ca-CaM-Phosphodiesterase
Calcium Calmodulin Dependent Phosphodiesterase
Calcium Calmodulin Stimulated Cyclic AMP Phosphodiesterase
Calcium-Calmodulin-Dependent Phosphodiesterase
Calcium-Calmodulin-Stimulated Cyclic AMP Phosphodiesterase
Calmodulin Dependent Phosphodiesterase
Calmodulin Dependent cGMP Phosphodiesterase
Calmodulin Phosphodiesterase
Calmodulin-Dependent Phosphodiesterase
Calmodulin-Dependent Phosphodiesterase 1A
Calmodulin-Dependent Phosphodiesterase 1B
Calmodulin-Dependent Phosphodiesterase 1C
Calmodulin-Dependent cGMP Phosphodiesterase
Cyclic Nucleotide Phosphodiesterase PDE1 Family
Cyclic Nucleotide Phosphodiesterases, Type 1A
Cyclic Nucleotide Phosphodiesterases, Type 1B
Cyclic Nucleotide Phosphodiesterases, Type 1C
Cyclic Nucleotide Phosphodiesterases, Type I
PDE1 Phosphodiesterases
Phosphodiesterase 1A, Calmodulin Dependent
Phosphodiesterase 1A, Calmodulin-Dependent
Phosphodiesterase 1B, Calmodulin Dependent
Phosphodiesterase 1B, Calmodulin-Dependent
Phosphodiesterase 1C, Calmodulin Dependent
Phosphodiesterase 1C, Calmodulin-Dependent
Phosphodiesterase, Calcium-Calmodulin-Dependent
Phosphodiesterase, Calmodulin-Dependent cGMP
Phosphodiesterases, PDE1
cGMP Phosphodiesterase, Calmodulin-Dependent
Tree number(s): D08.811.277.352.640.150.100
D08.811.277.352.640.155.100
D12.776.476.008.100
D12.776.476.009.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054677
Scope note: A CALCIUM and CALMODULIN-dependent cyclic nucleotide phosphodiesterase subfamily. The three members of this family are referred to as type 1A, type 1B, and type 1C and are each product of a distinct gene. In addition, multiple enzyme variants of each subtype can be produced due to multiple alternative mRNA splicing. Although the type 1 enzymes are classified as 3',5'-cyclic-AMP phosphodiesterases (EC 3.1.4.17), some members of this class have additional specificity for CYCLIC GMP.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.4.17
Previous Indexing: 3',5'-Cyclic-GMP Phosphodiesterases (1981-2007)
Public MeSH Note: 2008; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE I was indexed under PHOSPHORIC DIESTER HYDROLASES 1990-2007, for CA++ CALMODULIN DEPENDENT CYCLIC AMP PHOSPHODIESTERASE see 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1986-2007, for CALMODULIN PHOSPHODIESTERASE see 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1981-2007, for CALMODULIN-DEPENDENT PHOSPHODIESTERASE see 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1984-2007
History Note: 2008(1981) for CA++ CALMODULIN DEPENDENT CYCLIC AMP PHOSPHODIESTERASE use 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1986-2007, for CALMODULIN PHOSPHODIESTERASE use 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1981-2007, for CALMODULIN-DEPENDENT PHOSPHODIESTERASE use 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 1984-2007
DeCS ID: 52676
Unique ID: D054677
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2015/11/23
Cyclic Nucleotide Phosphodiesterases, Type 1 - Preferred
Concept UI M0177000
Scope note A CALCIUM and CALMODULIN-dependent cyclic nucleotide phosphodiesterase subfamily. The three members of this family are referred to as type 1A, type 1B, and type 1C and are each product of a distinct gene. In addition, multiple enzyme variants of each subtype can be produced due to multiple alternative mRNA splicing. Although the type 1 enzymes are classified as 3',5'-cyclic-AMP phosphodiesterases (EC 3.1.4.17), some members of this class have additional specificity for CYCLIC GMP.
Preferred term Cyclic Nucleotide Phosphodiesterases, Type 1
Entry term(s) Ca CaM Phosphodiesterase
Ca(2+)-CaM-Stimulated PDE
Ca++ Calmodulin Dependent Cyclic AMP Phosphodiesterase
Ca-CaM-Phosphodiesterase
Calcium Calmodulin Dependent Phosphodiesterase
Calcium Calmodulin Stimulated Cyclic AMP Phosphodiesterase
Calcium-Calmodulin-Dependent Phosphodiesterase
Calcium-Calmodulin-Stimulated Cyclic AMP Phosphodiesterase
Calmodulin Dependent Phosphodiesterase
Calmodulin Dependent cGMP Phosphodiesterase
Calmodulin Phosphodiesterase
Calmodulin-Dependent Phosphodiesterase
Calmodulin-Dependent cGMP Phosphodiesterase
Cyclic Nucleotide Phosphodiesterase PDE1 Family
Cyclic Nucleotide Phosphodiesterases, Type I
PDE1 Phosphodiesterases
Phosphodiesterase, Calcium-Calmodulin-Dependent
Phosphodiesterase, Calmodulin-Dependent cGMP
Phosphodiesterases, PDE1
cGMP Phosphodiesterase, Calmodulin-Dependent
Cyclic Nucleotide Phosphodiesterases, Type 1B - Narrower
Concept UI M0506859
Preferred term Cyclic Nucleotide Phosphodiesterases, Type 1B
Entry term(s) Calmodulin-Dependent Phosphodiesterase 1B
Phosphodiesterase 1B, Calmodulin Dependent
Phosphodiesterase 1B, Calmodulin-Dependent
Cyclic Nucleotide Phosphodiesterases, Type 1C - Narrower
Concept UI M0506860
Preferred term Cyclic Nucleotide Phosphodiesterases, Type 1C
Entry term(s) Calmodulin-Dependent Phosphodiesterase 1C
Phosphodiesterase 1C, Calmodulin Dependent
Phosphodiesterase 1C, Calmodulin-Dependent
Cyclic Nucleotide Phosphodiesterases, Type 1A - Narrower
Concept UI M0506858
Preferred term Cyclic Nucleotide Phosphodiesterases, Type 1A
Entry term(s) Calmodulin-Dependent Phosphodiesterase 1A
Phosphodiesterase 1A, Calmodulin Dependent
Phosphodiesterase 1A, Calmodulin-Dependent



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey