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Descriptor English: Steroidogenic Factor 1
Descriptor Spanish: Factor Esteroidogénico 1
Descriptor factor 1 esteroidogénico
Entry term(s) factor esteroidogénico 1
Scope note: Factor de transcripción y miembro de la familia de receptores nucleares NR5 que se expresa, durante el desarrollo, en los sistemas suprarrenal y reproductor. Tiene una función importante en la diferenciación sexual, la formación de tejidos esteroidogénicos primarios y sus funciones en las fases posnatal y adulta de la vida. Regula la expresión de enzimas esteroidogénicas fundamentales.
Descriptor Portuguese: Fator Esteroidogênico 1
Descriptor French: Facteur stéroïdogène-1
Entry term(s): AD4BP Protein
Ad4 Binding Protein
Ad4-Binding Protein
Adrenal 4 Binding Protein
FTZF1 Protein
Fushi Tarazu Factor Homolog 1
NR5A1 Protein
Nuclear Receptor 5A1 Protein
SF-1 Transcription Factor
Steroid Hormone Receptor Ad4BP
Transcription Factor, SF-1
Tree number(s): D12.776.826.925
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054339
Scope note: A transcription factor and member of the nuclear receptor family NR5 that is expressed throughout the adrenal and reproductive axes during development. It plays an important role in sexual differentiation, formation of primary steroidogenic tissues, and their functions in post-natal and adult life. It regulates the expression of key steroidogenic enzymes.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Homeodomain Proteins (1993-2007)
Receptors, Cytoplasmic and Nuclear (1993-2007)
Transcription Factors (1993-2007)
Public MeSH Note: 2008; STEROIDOGENIC FACTOR 1 was indexed under TRANSCRIPTION FACTORS; HOMEODOMAIN PROTEINS; & RECEPTORS, CYTOPLASMIC AND NUCLEAR 2004-2007
History Note: 2008
DeCS ID: 52827
Unique ID: D054339
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2015/06/23
Steroidogenic Factor 1 - Preferred
Concept UI M0205785
Scope note A transcription factor and member of the nuclear receptor family NR5 that is expressed throughout the adrenal and reproductive axes during development. It plays an important role in sexual differentiation, formation of primary steroidogenic tissues, and their functions in post-natal and adult life. It regulates the expression of key steroidogenic enzymes.
Preferred term Steroidogenic Factor 1
Entry term(s) AD4BP Protein
Ad4 Binding Protein
Ad4-Binding Protein
Adrenal 4 Binding Protein
FTZF1 Protein
Fushi Tarazu Factor Homolog 1
NR5A1 Protein
Nuclear Receptor 5A1 Protein
SF-1 Transcription Factor
Steroid Hormone Receptor Ad4BP
Transcription Factor, SF-1



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