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Descriptor English: Hepatocyte Nuclear Factor 4
Descriptor Spanish: Factor Nuclear 4 del Hepatocito
Descriptor factor nuclear 4 del hepatocito
Scope note: Subfamilia de receptores nucleares que regulan la TRANSCRIPCIÓN de un grupo diverso de GENES implicados en la síntesis de FACTORES DE COAGULACIÓN SANGUÍNEA y en el metabolismo de la GLUCOSA, el COLESTEROL y los ÁCIDOS GRASOS.
Descriptor Portuguese: Fator 4 Nuclear de Hepatócito
Descriptor French: Facteur nucléaire hépatocytaire HNF-4
Entry term(s): HNF4 Transcription Factor
Hepatocyte Nuclear Factor 4 alpha
Hepatocyte Nuclear Factor 4 beta
Hepatocyte Nuclear Factor 4 gamma
Hepatocyte Nuclear Factor 4-alpha
Hepatocyte Nuclear Factor 4-beta
Hepatocyte Nuclear Factor 4-gamma
Hepatocyte Nuclear Factor Forkhead Homolog 4
Hepatocyte Nuclear Factor-Forkhead Homolog 4
Nuclear Receptor Subfamily 2 Group A, Member 2
Nuclear Receptor Subfamily 2, Group A, Member 1
Transcription Factor, HNF4
Tree number(s): D12.776.260.262.968
D12.776.660.352.968
D12.776.826.119
D12.776.930.318.968
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051557
Scope note: A subfamily of nuclear receptors that regulate GENETIC TRANSCRIPTION of a diverse group of GENES involved in the synthesis of BLOOD COAGULATION FACTORS; and in GLUCOSE; CHOLESTEROL; and FATTY ACIDS metabolism.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; HEPATOCYTE NUCLEAR FACTOR 4 was indexed under DNA-BINDING PROTEINS, PHOSPHOPROTEINS & TRANSCRIPTION FACTORS 1991-2005
History Note: 2006 (1991)
DeCS ID: 51002
Unique ID: D051557
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/06/30
Hepatocyte Nuclear Factor 4 - Preferred
Concept UI M0184201
Scope note A subfamily of nuclear receptors that regulate GENETIC TRANSCRIPTION of a diverse group of GENES involved in the synthesis of BLOOD COAGULATION FACTORS; and in GLUCOSE; CHOLESTEROL; and FATTY ACIDS metabolism.
Preferred term Hepatocyte Nuclear Factor 4
Entry term(s) HNF4 Transcription Factor
Hepatocyte Nuclear Factor Forkhead Homolog 4
Hepatocyte Nuclear Factor-Forkhead Homolog 4
Transcription Factor, HNF4
Hepatocyte Nuclear Factor 4-gamma - Narrower
Concept UI M0362150
Preferred term Hepatocyte Nuclear Factor 4-gamma
Entry term(s) Hepatocyte Nuclear Factor 4 gamma
Nuclear Receptor Subfamily 2 Group A, Member 2
Hepatocyte Nuclear Factor 4-alpha - Narrower
Concept UI M0480926
Preferred term Hepatocyte Nuclear Factor 4-alpha
Entry term(s) Hepatocyte Nuclear Factor 4 alpha
Nuclear Receptor Subfamily 2, Group A, Member 1
Hepatocyte Nuclear Factor 4-beta - Narrower
Concept UI M0480993
Preferred term Hepatocyte Nuclear Factor 4-beta
Entry term(s) Hepatocyte Nuclear Factor 4 beta



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