| Descriptor English: | Liver X Receptors | ||||||
| Descriptor Spanish: |
Receptores X del Hígado
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| Descriptor Portuguese: | Receptores X do Fígado | ||||||
| Descriptor French: | Récepteurs hépatiques X | ||||||
| Entry term(s): |
LXR Alpha Protein LXR-Alpha Protein LXR-Alpha, Oxysterols Receptor LXR-Beta, Oxysterols Receptor LXRalpha Protein LXRbeta Protein Liver X Receptor Liver X Receptor Alpha Liver X Receptor Beta Liver X Receptor-Alpha Liver X Receptor-Beta NR1H2 Protein NR1H3 Protein Nuclear Orphan Receptor LXR Alpha Nuclear Orphan Receptor LXR-Alpha Nuclear Oxysterol Receptors Nuclear Receptor Subfamily 1, Group H, Member 2 Nuclear Receptor Subfamily 1, Group H, Member 3 Oxysterol Receptors, Nuclear Oxysterols Receptor LXR Alpha Oxysterols Receptor LXR Beta Oxysterols Receptor LXR-Alpha Oxysterols Receptor LXR-Beta |
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| Tree number(s): |
D12.776.260.531 D12.776.826.194 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000071518 | ||||||
| Scope note: | Nuclear receptors that bind OXYSTEROLS and function as heterodimers with RETINOID X RECEPTORS. They have important functions in regulating cholesterol homeostasis, ENERGY METABOLISM; INFLAMMATION; and the immune response. |
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| Allowable Qualifiers: |
AD administration & dosage AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CH chemistry CL classification DE drug effects DF deficiency GE genetics HI history IM immunology IP isolation & purification ME metabolism PH physiology RE radiation effects TU therapeutic use UL ultrastructure |
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| Public MeSH Note: | 2017; LIVER X RECEPTORS was indexed under ORPHAN NUCLEAR RECEPTORS 2009-2016; and under DNA-BINDING PROTEINS and RECEPTORS, CYTOPLASMIC AND NUCLEAR 2002-2009 |
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| History Note: | 2017 (2002) |
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| DeCS ID: | 56605 | ||||||
| Unique ID: | D000071518 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/08 | ||||||
| Revision Date: | 2016/04/20 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Liver X Receptors
- Preferred
Liver X Receptor Alpha
- Narrower
Liver X Receptor Beta
- Narrower
| Concept UI |
M000614997 |
| Scope note | Nuclear receptors that bind OXYSTEROLS and function as heterodimers with RETINOID X RECEPTORS. They have important functions in regulating cholesterol homeostasis, ENERGY METABOLISM; INFLAMMATION; and the immune response. |
| Preferred term | Liver X Receptors |
| Entry term(s) |
Liver X Receptor Nuclear Oxysterol Receptors Oxysterol Receptors, Nuclear |
| Concept UI |
M0246645 |
| Scope note | A liver X receptor that is expressed primarily by cells in the liver and other metabolically-active tissues. |
| Preferred term | Liver X Receptor Alpha |
| Entry term(s) |
LXR Alpha Protein LXR-Alpha Protein LXR-Alpha, Oxysterols Receptor LXRalpha Protein Liver X Receptor-Alpha NR1H3 Protein Nuclear Orphan Receptor LXR Alpha Nuclear Orphan Receptor LXR-Alpha Nuclear Receptor Subfamily 1, Group H, Member 3 Oxysterols Receptor LXR Alpha Oxysterols Receptor LXR-Alpha |
| Concept UI |
M000614998 |
| Scope note | A liver X receptor that is ubiquitously expressed. Loss of LXR-beta function is associated with an increase in the expression of UNCOUPLING PROTEIN 1 as well as OBESITY. |
| Preferred term | Liver X Receptor Beta |
| Entry term(s) |
LXR-Beta, Oxysterols Receptor LXRbeta Protein Liver X Receptor-Beta NR1H2 Protein Nuclear Receptor Subfamily 1, Group H, Member 2 Oxysterols Receptor LXR Beta Oxysterols Receptor LXR-Beta |
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