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Descriptor English: Polycomb Repressive Complex 2
Descriptor Spanish: Complejo Represivo Polycomb 2
Descriptor complejo represivo polycomb 2
Entry term(s) complejo 2 polycomb represivo
Scope note: Multisubunidad del complejo proteico policomb, que cataliza la METILACION de la HISTONA H3 cromosómica. Actúa conjuntamente con el COMPLEJO 2 POLICOMB REPRESIVO en la REPRESIÓN EPIGENÉTICA.
Descriptor Portuguese: Complexo Repressor Polycomb 2
Descriptor French: Complexe répresseur Polycomb-2
Tree number(s): D05.500.781.750
D08.811.913.555.500.800.200.500.500
D12.776.660.235.600.200
D12.776.664.235.800.200
D12.776.930.780.890.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D063151
Scope note: A multisubunit polycomb protein complex that catalyzes the METHYLATION of chromosomal HISTONE H3. It works in conjunction with POLYCOMB REPRESSIVE COMPLEX 1 to effect EPIGENETIC REPRESSION.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.1.1.43
Previous Indexing: Repressor Proteins (1998-2012)
Transcription Factors (1997)
Public MeSH Note: 2013
History Note: 2013
DeCS ID: 54922
Unique ID: D063151
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2018/01/16
Polycomb Repressive Complex 2 - Preferred
Concept UI M0499463
Scope note A multisubunit polycomb protein complex that catalyzes the METHYLATION of chromosomal HISTONE H3. It works in conjunction with POLYCOMB REPRESSIVE COMPLEX 1 to effect EPIGENETIC REPRESSION.
Preferred term Polycomb Repressive Complex 2



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