Search
Descriptor English: Polycomb Repressive Complex 1
Descriptor Spanish: Complejo Represivo Polycomb 1
Descriptor complejo represivo polycomb 1
Entry term(s) complejo 1 polycomb represivo
Scope note: Subunidad del complejo proteico policomb, con afinidad por la CROMATINA que contiene HISTONA H3 metilada. Contiene una ubiquitina ligasa E3 específica para la HISTONA H2A y actúa conjuntamente con el COMPLEJO 2 POLICOMB REPRESIVO en la REPRESIÓN EPIGENÉTICA.
Descriptor Portuguese: Complexo Repressor Polycomb 1
Descriptor French: Complexe répresseur Polycomb-1
Tree number(s): D05.500.781.100
D08.811.464.938.750.280
D12.776.660.235.600.100
D12.776.664.235.800.100
D12.776.930.780.890.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D063150
Scope note: A multisubunit polycomb protein complex with affinity for CHROMATIN that contains methylated HISTONE H3. It contains an E3 ubiquitin ligase activity that is specific for HISTONE H2A and works in conjunction with POLYCOMB REPRESSIVE COMPLEX 2 to effect EPIGENETIC REPRESSION.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.3.2.27
Previous Indexing: Repressor Proteins (1998-2012)
Transcription Factors (1997)
Public MeSH Note: 2013
History Note: 2013
DeCS ID: 54921
Unique ID: D063150
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2016/06/02
Polycomb Repressive Complex 1 - Preferred
Concept UI M0499462
Scope note A multisubunit polycomb protein complex with affinity for CHROMATIN that contains methylated HISTONE H3. It contains an E3 ubiquitin ligase activity that is specific for HISTONE H2A and works in conjunction with POLYCOMB REPRESSIVE COMPLEX 2 to effect EPIGENETIC REPRESSION.
Preferred term Polycomb Repressive Complex 1



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey