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Descriptor English: Minichromosome Maintenance Complex Component 3
Descriptor Spanish: Componente 3 del Complejo de Mantenimiento de Minicromosoma
Descriptor componente 3 del complejo de mantenimiento de minicromosomas
Scope note: Proteína de mantenimiento del minicromosoma que es un componente clave de los seis miembros del complejo de proteínas MCM. Contiene una SEÑAL DE LOCALIZACIÓN NUCLEAR que puede actuar como diana para el complejo proteico. Además, la acetilación de esta proteína posiblemente juegue un papel en la regulación de la replicación del ADN y el progreso del ciclo celular.
Descriptor Portuguese: Componente 3 do Complexo de Manutenção de Minicromossomo
Descriptor French: Composant-3 du complexe de maintenance des minichromosomes
Entry term(s): DNA Polymerase alpha Holoenzyme associated Protein P1
DNA Polymerase alpha Holoenzyme-associated Protein P1
DNA Replication Licensing Factor MCM3
RLF Subunit beta
Subunit beta, RLF
beta, RLF Subunit
Tree number(s): D08.811.277.040.025.159.186.300
D08.811.399.340.186.300
D12.776.167.409.300
D12.776.660.235.500.300
D12.776.664.235.750.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064126
Scope note: A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It contains a NUCLEAR LOCALIZATION SIGNAL, which provide targeting of the protein complex. In addition, acetylation of this protein may play a role in regulating of DNA replication and cell cycle progression.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.4.12
Previous Indexing: Cell Cycle Proteins (1990-2013)
DNA-Binding Proteins (1990-2013)
Nuclear Proteins (1990-2013)
Public MeSH Note: 2014
History Note: 2014
DeCS ID: 55259
Unique ID: D064126
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Minichromosome Maintenance Complex Component 3 - Preferred
Concept UI M0579722
Scope note A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It contains a NUCLEAR LOCALIZATION SIGNAL, which provide targeting of the protein complex. In addition, acetylation of this protein may play a role in regulating of DNA replication and cell cycle progression.
Preferred term Minichromosome Maintenance Complex Component 3
Entry term(s) DNA Polymerase alpha Holoenzyme associated Protein P1
DNA Polymerase alpha Holoenzyme-associated Protein P1
DNA Replication Licensing Factor MCM3
RLF Subunit beta
Subunit beta, RLF
beta, RLF Subunit



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