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Descriptor English: Minichromosome Maintenance Proteins
Descriptor Spanish: Proteínas de Mantenimiento de Minicromosoma
Descriptor proteínas de mantenimiento de minicromosomas
Scope note: Familia de proteínas que en un principio fueron identificadas en el SACCHAROMYCES CEREVISIAE como elementos esenciales para el mantenimiento de la estructura de microcromosomas00. Dichas proteínas forman un complejo con actividad helicasa e intervienen en diversas funciones relacionadas con el ADN, incluida la replicación de la elongación, la trascripción de ARN, la remodelación de la cromatina y la estabilidad del genoma.
Descriptor Portuguese: Proteínas de Manutenção de Minicromossomo
Descriptor French: Protéines de maintenance des minichromosomes
Entry term(s): Helicase, MCM2-7
MCM Protein Complex
MCM2 7 Complex
MCM2 7 Helicase
MCM2-7 Complex
MCM2-7 Helicase
Maintenance Proteins, Minichromosome
Tree number(s): D08.811.277.040.025.159.186
D08.811.399.340.186
D12.776.167.409
D12.776.660.235.500
D12.776.664.235.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064110
Scope note: A family of proteins that were originally identified in SACCHAROMYCES CEREVISIAE as being essential for maintaining the structure of minichromosomes00. They form into a protein complex that has helicase activity and is involved in a variety of DNA-related functions including replication elongation, RNA transcription, chromatin remodeling, and genome stability.
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.4.12
Public MeSH Note: 2014
History Note: 2014
DeCS ID: 55257
Unique ID: D064110
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Minichromosome Maintenance Proteins - Preferred
Concept UI M0579688
Scope note A family of proteins that were originally identified in SACCHAROMYCES CEREVISIAE as being essential for maintaining the structure of minichromosomes00. They form into a protein complex that has helicase activity and is involved in a variety of DNA-related functions including replication elongation, RNA transcription, chromatin remodeling, and genome stability.
Preferred term Minichromosome Maintenance Proteins
Entry term(s) Maintenance Proteins, Minichromosome
MCM Protein Complex - Narrower
Concept UI M0579691
Scope note A hexameric protein complex of minichromosome maintenance proteins.
Preferred term MCM Protein Complex
Entry term(s) Helicase, MCM2-7
MCM2 7 Complex
MCM2 7 Helicase
MCM2-7 Complex
MCM2-7 Helicase



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