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Descriptor English: Minichromosome Maintenance Complex Component 8
Descriptor Spanish: Componente 8 del Complejo de Mantenimiento de Minicromosoma
Descriptor componente 8 del complejo de mantenimiento de minicromosomas
Scope note: Proteína de mantenimiento del minicromosoma que forma un complejo hexamérico con el COMPONENTE 9 DEL COMPLEJO DE MANTENIMIENTO DEL MINICROMOSOMA. El complejo helicasa MCM8-MCM9 está relacionado con la REPARACIÓN DE RECOMBINACIÓN HOMOLOGA que sigue a la formación de uniones cruzadas entre las hebras de ADN.
Descriptor Portuguese: Componente 8 do Complexo de Manutenção de Minicromossomo
Descriptor French: Composant-8 du complexe de maintenance des minichromosomes
Entry term(s): DNA Replication Licensing Factor MCM8
Tree number(s): D08.811.277.040.025.159.186.800
D08.811.399.340.186.800
D12.776.167.409.800
D12.776.660.235.500.800
D12.776.664.235.750.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064187
Scope note: A minichromosome maintenance protein that forms a hexameric complex with MINICHROMSOME MAINTENANCE COMPLEX COMPONENT 9. The MCM8-MCM9 helicase complex is involved in HOMOLOGOUS RECOMBINATION REPAIR following the formation of DNA interstrand cross-links.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.4.12
Previous Indexing: Cell Cycle Proteins (2005-2013)
DNA-Binding Proteins (2005-2013)
Public MeSH Note: 2014
History Note: 2014
DeCS ID: 55264
Unique ID: D064187
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Minichromosome Maintenance Complex Component 8 - Preferred
Concept UI M0580137
Scope note A minichromosome maintenance protein that forms a hexameric complex with MINICHROMSOME MAINTENANCE COMPLEX COMPONENT 9. The MCM8-MCM9 helicase complex is involved in HOMOLOGOUS RECOMBINATION REPAIR following the formation of DNA interstrand cross-links.
Preferred term Minichromosome Maintenance Complex Component 8
Entry term(s) DNA Replication Licensing Factor MCM8



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