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Descriptor English: Minichromosome Maintenance Complex Component 5
Descriptor Spanish: Componente 5 del Complejo de Mantenimiento de Minicromosoma
Descriptor componente 5 del complejo de mantenimiento de minicromosomas
Scope note: Proteína de mantenimiento del minicromosoma que es un componente clave de los seis miembros del complejo de proteínas MCM. Además, la interacción de esta proteína con ciclina A provoca su reclutamiento hacia los CENTROSOMAS, donde juega un papel en el control de la reduplicación del centrosoma.
Descriptor Portuguese: Componente 5 do Complexo de Manutenção de Minicromossomo
Descriptor French: Composant-5 du complexe de maintenance des minichromosomes
Entry term(s): CDC46 Protein
DNA Replication Licensing Factor MCM5
Tree number(s): D08.811.277.040.025.159.186.500
D08.811.399.340.186.500
D12.776.167.409.500
D12.776.660.235.500.500
D12.776.664.235.750.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064150
Scope note: A minichromosome maintenance protein that is a key component of the six member MCM protein complex. In addition, interaction of this protein with cyclin A results in its recruitment to CENTROSOMES where it may play a role in controlling centrosome reduplication.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.4.12
Previous Indexing: Cell Cycle Proteins (2004-2013)
Public MeSH Note: 2014
History Note: 2014
DeCS ID: 55261
Unique ID: D064150
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Minichromosome Maintenance Complex Component 5 - Preferred
Concept UI M0579840
Scope note A minichromosome maintenance protein that is a key component of the six member MCM protein complex. In addition, interaction of this protein with cyclin A results in its recruitment to CENTROSOMES where it may play a role in controlling centrosome reduplication.
Preferred term Minichromosome Maintenance Complex Component 5
Entry term(s) CDC46 Protein
DNA Replication Licensing Factor MCM5



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