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Descriptor English: ATP Binding Cassette Transporter, Subfamily G
Descriptor Spanish: Transportador de Casetes de Unión a ATP, Subfamilia G
Descriptor transportador de casetes de unión a ATP, subfamilia G
Entry term(s) proteínas ABCG
subfamilia G de transportadores de casetes de unión al ATP
subfamilia G de transportadores de casetes de unión de ATP
transportador ABCG
transportador de casete de unión a ATP, subfamilia G
transportadores ABCG
transportadores de casete de unión a ATP, subfamilia G
transportadores de casetes de unión a ATP, subfamilia G
transportadores de casetes de unión al ATP, subfamilia G
Scope note: Subfamilia de transportadores de casetes de unión a ATP que funciona principalmente en el transporte de lípidos y ESTEROLES a través de la MEMBRANA CELULAR. También exporta UREA y varios fármacos dando lugar a RESISTENCIA A MÚLTIPLES MEDICAMENTOS. Son más pequeños que las otras proteínas de casetes de unión a ATP, constan de seis hélices alfa transmembranarias y un dominio distintivo de unión a ATP citoplasmático N-terminal y funcionan como homo o heterodímeros junto con otros transportadores ABCG.
Descriptor Portuguese: Subfamília G de Transportadores de Cassetes de Ligação de ATP
Descriptor French: Sous-famille G des transporteurs à cassette liant l'ATP
Entry term(s): ABCG Proteins
ABCG Transporter
ABCG Transporters
ATP Binding Cassette Transporter, Sub Family G
ATP Binding Cassette Transporter, Sub-Family G
Tree number(s): D09.400.430.890.020.457
D12.776.157.530.100.228
D12.776.395.550.020.457
D12.776.543.550.192.457
D12.776.543.585.100.228
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000070996
Scope note: A subfamily of ATP binding cassette transporters that function primarily in the transport of lipids and STEROLS across the CELL MEMBRANE. They also export UREA and various drugs resulting in MULTIDRUG RESISTANCE. They are smaller than most other ATP binding cassette proteins, consisting of six transmembrane alpha helices and a distinct N-terminal cytoplasmic ATP-binding domain, and function as homo- or heterodimers with other ABCG transporters.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: ATP-Binding Cassette Transporters (2001-2016)
Public MeSH Note: 2019; see ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY G 2017-2018
History Note: 2019 (2017)
DeCS ID: 56577
Unique ID: D000070996
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2018/02/28
ATP Binding Cassette Transporter, Subfamily G - Preferred
Concept UI M000612842
Scope note A subfamily of ATP binding cassette transporters that function primarily in the transport of lipids and STEROLS across the CELL MEMBRANE. They also export UREA and various drugs resulting in MULTIDRUG RESISTANCE. They are smaller than most other ATP binding cassette proteins, consisting of six transmembrane alpha helices and a distinct N-terminal cytoplasmic ATP-binding domain, and function as homo- or heterodimers with other ABCG transporters.
Preferred term ATP Binding Cassette Transporter, Subfamily G
Entry term(s) ABCG Proteins
ABCG Transporter
ABCG Transporters
ATP Binding Cassette Transporter, Sub Family G
ATP Binding Cassette Transporter, Sub-Family G



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