| Descriptor English: | S100 Calcium-Binding Protein A4 | ||||||
| Descriptor Spanish: |
Proteína de Unión al Calcio S100A4
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| Descriptor Portuguese: | Proteína A4 de Ligação a Cálcio da Família S100 | ||||||
| Descriptor French: | Protéine S100A4 liant le calcium | ||||||
| Entry term(s): |
Calcium-Binding Protein, Placental Calvasculin Protein Fibroblast Specific Protein 1 Fibroblast-Specific Protein 1 Metastasin Protein Placental Calcium Binding Protein Placental Calcium-Binding Protein S100 Calcium Binding Protein A4 S100A4 Protein |
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| Tree number(s): |
D12.776.157.125.750.813 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000071999 | ||||||
| Scope note: | An S100 protein characterized by four helix bundles that form N- and C-terminal EF HAND MOTIFS. It functions as a homodimer and interacts with both intracellular and extracellular signaling proteins. Aberrant S100A4 activity is associated with NEOPLASM METASTASIS; FIBROSIS; and RHEUMATOID ARTHRITIS. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Calcium-Binding Proteins (1992-2016) S100 Proteins (2003-2016) |
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| Public MeSH Note: | 2017 |
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| History Note: | 2017 |
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| DeCS ID: | 56564 | ||||||
| Unique ID: | D000071999 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/08 | ||||||
| Revision Date: | 2016/05/27 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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S100 Calcium-Binding Protein A4
- Preferred
| Concept UI |
M000616196 |
| Scope note | An S100 protein characterized by four helix bundles that form N- and C-terminal EF HAND MOTIFS. It functions as a homodimer and interacts with both intracellular and extracellular signaling proteins. Aberrant S100A4 activity is associated with NEOPLASM METASTASIS; FIBROSIS; and RHEUMATOID ARTHRITIS. |
| Preferred term | S100 Calcium-Binding Protein A4 |
| Entry term(s) |
Calcium-Binding Protein, Placental Calvasculin Protein Fibroblast Specific Protein 1 Fibroblast-Specific Protein 1 Metastasin Protein Placental Calcium Binding Protein Placental Calcium-Binding Protein S100 Calcium Binding Protein A4 S100A4 Protein |
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