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Descriptor English: Filaggrin Proteins
Descriptor Spanish: Proteínas Filagrina
Descriptor proteínas filagrinas
Entry term(s) filagrina
precursor de la proteína básica del estrato córneo
profilagrina
proteína básica del estrato córneo
proteína filagrina
Scope note: Proteínas S100 que agregan QUERATINAS. Las proteínas precursoras de filagrina se encuentran en gránulos de queratohialina y se procesan en moléculas funcionales individuales de filagrina durante la diferenciación terminal de la epidermis. Las mutaciones en las filagrinas se asocian a ICTIOSIS VULGAR.
Descriptor Portuguese: Proteínas Filagrinas
Descriptor French: Protéines filaggrine
Entry term(s): Filaggrin
Filaggrin Protein
Profilaggrin
Protein, Filaggrin
Proteins, Filaggrin
Stratum Corneum Basic Protein
Stratum Corneum Basic Protein Precursor
Tree number(s): D12.776.157.125.750.250
D12.776.631.658.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000091344
Scope note: S100 proteins that aggregate KERATINS. Filaggrin precursor proteins are localized in keratohyalin granules and processed into individual functional filaggrin molecules during terminal epidermis differentiation. Mutations in fillagrins are associated with ICHTHYOSIS VULGARIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Intermediate Filament Proteins (1982-2021)
Public MeSH Note: 2022; FILAGRIN was indexed under INTERMEDIATE FILAMENT PROTEINS 1984-2021; and under PROTEINS 1981-1983
History Note: 2022(1981)
DeCS ID: 59865
Unique ID: D000091344
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/06/30
Filaggrin Proteins - Preferred
Concept UI M000748545
Scope note S100 proteins that aggregate KERATINS. Filaggrin precursor proteins are localized in keratohyalin granules and processed into individual functional filaggrin molecules during terminal epidermis differentiation. Mutations in fillagrins are associated with ICHTHYOSIS VULGARIS.
Preferred term Filaggrin Proteins
Entry term(s) Filaggrin
Filaggrin Protein
Protein, Filaggrin
Proteins, Filaggrin
Stratum Corneum Basic Protein
Profilaggrin - Narrower
Concept UI M000748585
Preferred term Profilaggrin
Entry term(s) Stratum Corneum Basic Protein Precursor



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