| Descriptor English: | S100 Calcium Binding Protein A7 | ||||||
| Descriptor Spanish: |
Proteína A7 de Unión a Calcio de la Familia S100
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| Descriptor Portuguese: | Proteína A7 Ligante de Cálcio S100 | ||||||
| Descriptor French: | Protéine S100 de type A7 liant le calcium | ||||||
| Entry term(s): |
Psoriasin S100 A7 Protein S100-A7 Protein S100A7 Protein |
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| Tree number(s): |
D12.776.157.125.750.563 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000075023 | ||||||
| Scope note: | An S100 calcium binding protein that contains two EF HAND MOTIFS and also binds zinc. It is secreted via a non-classical secretory pathway and expressed by KERATINOCYTES and epithelial cells of the tongue. It has antimicrobial and immunomodulatory activities and is highly expressed in the skin of patients with PSORIASIS, as well as in bladder and skin epithelial carcinomas. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Calcium-Binding Proteins (1994-2017) S100 Proteins (2010-2017) |
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| Public MeSH Note: | 2018 |
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| History Note: | 2018 |
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| DeCS ID: | 57070 | ||||||
| Unique ID: | D000075023 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2017/05/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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S100 Calcium Binding Protein A7
- Preferred
| Concept UI |
M000628895 |
| Scope note | An S100 calcium binding protein that contains two EF HAND MOTIFS and also binds zinc. It is secreted via a non-classical secretory pathway and expressed by KERATINOCYTES and epithelial cells of the tongue. It has antimicrobial and immunomodulatory activities and is highly expressed in the skin of patients with PSORIASIS, as well as in bladder and skin epithelial carcinomas. |
| Preferred term | S100 Calcium Binding Protein A7 |
| Entry term(s) |
Psoriasin S100 A7 Protein S100-A7 Protein S100A7 Protein |
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