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Descriptor English: Endoglin
Descriptor Spanish: Endoglina
Descriptor endoglina
Entry term(s) antígeno CD105
proteína endoglina
Scope note: Glucoproteína de la membrana y FACTOR ANGIOGÉNICO que se expresa en las células del ENDOTELIO VASCULAR, el MÚSCULO LISO VASCULAR y los MONOCITOS. Funciona como correceptor para el FACTOR DE CRECIMIENTO TRANSFORMADOR BETA y modula la ADHESIÓN CELULAR. Las mutaciones en el gen de la endoglina se asocian a casos de TELANGIECTASIA HEMORRÁGICA HEREDITARIA.
Descriptor Portuguese: Endoglina
Descriptor French: Endogline
Entry term(s): Antigen, CD105
CD105 Antigen
Endoglin Protein
Tree number(s): D12.776.543.750.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071063
Scope note: A membrane glycoprotein and ANGIOGENESIS FACTOR that is expressed by cells of the VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; and MONOCYTES. It functions as a co-receptor for TRANSFORMING GROWTH FACTOR BETA and modulates CELL ADHESION. Mutations in the endoglin gene are associated with cases of HEREDITARY HEMORRHAGIC TELANGIECTASIA.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Antigens, CD (2006-2016)
Receptors, Cell Surface (2006-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56643
Unique ID: D000071063
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2017/05/24
Endoglin - Preferred
Concept UI M000612982
Scope note A membrane glycoprotein and ANGIOGENESIS FACTOR that is expressed by cells of the VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; and MONOCYTES. It functions as a co-receptor for TRANSFORMING GROWTH FACTOR BETA and modulates CELL ADHESION. Mutations in the endoglin gene are associated with cases of HEREDITARY HEMORRHAGIC TELANGIECTASIA.
Preferred term Endoglin
Entry term(s) Antigen, CD105
CD105 Antigen
Endoglin Protein



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