| Descriptor English: | BTB-POZ Domain | ||||||
| Descriptor Spanish: |
Dominio BTB-POZ
| ||||||
| Descriptor Portuguese: | Domínio BTB-POZ | ||||||
| Descriptor French: | Domaine BTB-POZ | ||||||
| Entry term(s): |
BTB (POZ) Domain BTB Domain BTB Domains BTB POZ Domain BTB-POZ Domains Broad Complex, Tramtrack and Bric a Brac Domain Broad-Complex, Tramtrack and Bric a Brac Domain POZ Domain POZ Domains POxvirus and Zinc Finger Domain |
||||||
| Tree number(s): |
G02.111.570.820.709.275.750.500.343 |
||||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000071757 | ||||||
| Scope note: | A homodimerization protein interaction domain occurring at the N terminus of proteins that contain multiple copies of either CYS2-HIS2 ZINC FINGERS or KELCH REPEATS. It is characterized by a tightly intertwined dimer with an extensive hydrophobic interface. A surface-exposed groove lined with conserved amino acids is formed at the dimer interface, suggesting a peptide-binding site. Many BTB proteins are transcriptional regulators that are thought to regulate CHROMATIN structure. |
||||||
| Allowable Qualifiers: |
DE drug effects GE genetics IM immunology PH physiology RE radiation effects |
||||||
| Previous Indexing: |
Amino Acid Sequence (1994-2016) DNA-Binding Proteins (1994-2016) Protein Structure, Tertiary (1995-2016) |
||||||
| Public MeSH Note: | 2017 |
||||||
| History Note: | 2017 |
||||||
| DeCS ID: | 56744 | ||||||
| Unique ID: | D000071757 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/08 | ||||||
| Revision Date: | 2016/05/09 |
-
-
PHENOMENA AND PROCESSES
Chemical Phenomena [G02]Chemical Phenomena
|
|
BTB-POZ Domain
- Preferred
| Concept UI |
M000615510 |
| Scope note | A homodimerization protein interaction domain occurring at the N terminus of proteins that contain multiple copies of either CYS2-HIS2 ZINC FINGERS or KELCH REPEATS. It is characterized by a tightly intertwined dimer with an extensive hydrophobic interface. A surface-exposed groove lined with conserved amino acids is formed at the dimer interface, suggesting a peptide-binding site. Many BTB proteins are transcriptional regulators that are thought to regulate CHROMATIN structure. |
| Preferred term | BTB-POZ Domain |
| Entry term(s) |
BTB (POZ) Domain BTB Domain BTB Domains BTB POZ Domain BTB-POZ Domains Broad Complex, Tramtrack and Bric a Brac Domain Broad-Complex, Tramtrack and Bric a Brac Domain POZ Domain POZ Domains POxvirus and Zinc Finger Domain |
We want your feedback on the new DeCS / MeSH website
We invite you to complete a survey that will take no more than 3 minutes.
Go to survey
