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Descriptor English: RING Finger Domains
Descriptor Spanish: Dominios RING Finger
Descriptor dominios en dedos de tipo RING
Entry term(s) dedos de zinc tipo RING
dominio RING finger
dominios dedos de cinc de tipo RING
dominios dedos de tipo RING
motivos dedos de cinc de tipo RING
motivos dedos de tipo RING
Scope note: Dominio de unión al cinc definido por la secuencia cisteína-X2-cisteína-X(9-39)-cisteína-X(l-3)-His-X(2-3)-cisteína-X2-cisteína-X(4-48)-cisteína-X2-cisteína, en donde X es cualquier aminoácido. El motivo en dedo de tipo RING une dos átomos de cinc, y cada átomo de cinc está unido tetraédricamente, ya sea por cuatro cisteínas o por tres cisteínas y una histidina. El motivo también forma una estructura unitaria con una región central de central en cruz y se encuentra en muchas proteínas que se hallan implicadas en las interacciones entre proteínas. El acrónimo RING representa Really Interesting New Gene.
Descriptor Portuguese: Domínios RING Finger
Descriptor French: Domaines à doigts de zinc de type RING
Entry term(s): Domains, RING Finger
RING Finger Domain
RING Finger Motif
RING Finger Motifs
Tree number(s): G02.111.570.820.709.275.500.985.500
G02.111.570.820.709.275.750.500.625
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054829
Scope note: A zinc-binding domain defined by the sequence Cysteine-X2-Cysteine-X(9-39)-Cysteine-X(l-3)-His-X(2-3)-Cysteine-X2-Cysteine -X(4-48)-Cysteine-X2-Cysteine, where X is any amino acid. The RING finger motif binds two atoms of zinc, with each zinc atom ligated tetrahedrally by either four cysteines or three cysteines and a histidine. The motif also forms into a unitary structure with a central cross-brace region and is found in many proteins that are involved in protein-protein interactions. The acronym RING stands for Really Interesting New Gene.
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Public MeSH Note: 2008
History Note: 2008
DeCS ID: 52897
Unique ID: D054829
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2016/05/31
RING Finger Domains - Preferred
Concept UI M0508104
Scope note A zinc-binding domain defined by the sequence Cysteine-X2-Cysteine-X(9-39)-Cysteine-X(l-3)-His-X(2-3)-Cysteine-X2-Cysteine -X(4-48)-Cysteine-X2-Cysteine, where X is any amino acid. The RING finger motif binds two atoms of zinc, with each zinc atom ligated tetrahedrally by either four cysteines or three cysteines and a histidine. The motif also forms into a unitary structure with a central cross-brace region and is found in many proteins that are involved in protein-protein interactions. The acronym RING stands for Really Interesting New Gene.
Preferred term RING Finger Domains
Entry term(s) Domains, RING Finger
RING Finger Domain
RING Finger Motif
RING Finger Motifs



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