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Descriptor English: AAA Proteins
Descriptor Spanish: Proteínas AAA
Descriptor proteínas AAA
Entry term(s) NTPasas P-loop
NTPasas de bucle P
proteína AAA
superfamilia AAA
superfamilia AAA+
Scope note: Amplia superfamilia, altamente conservada y funcionalmente diversa, de proteínas NTPasas y de unión a nucleótidos, que se caracterizan por un dominio conservado de 200-250 aminoácidos, catalítico y de unión a nucleótidos, el módulo AAA+. Se ensamblan en complejos anulares hexaméricos que intervienen en la remodelación de macromoléculas dependiente de energía. Entre sus miembros se incluyen las ATPASAS ASOCIADAS CON ACTIVIDADES CELULARES DIVERSAS.
Descriptor Portuguese: Proteínas AAA
Descriptor French: Protéines AAA
Entry term(s): AAA Protein
AAA Superfamily
AAA+ Superfamily
NTPases, P-Loop
P Loop NTPases
P-Loop NTPases
Superfamily, AAA
Superfamily, AAA+
Tree number(s): D08.811.277.040.013
D12.776.157.025
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000074582
Scope note: A large, highly conserved and functionally diverse superfamily of NTPases and nucleotide-binding proteins that are characterized by a conserved 200 to 250 amino acid nucleotide-binding and catalytic domain, the AAA+ module. They assemble into hexameric ring complexes that function in the energy-dependent remodeling of macromolecules. Members include ATPASES ASSOCIATED WITH DIVERSE CELLULAR ACTIVITIES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.4.-
Previous Indexing: Adenosine Triphosphatases (1995-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 56992
Unique ID: D000074582
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/04/05
AAA Proteins - Preferred
Concept UI M000626837
Scope note A large, highly conserved and functionally diverse superfamily of NTPases and nucleotide-binding proteins that are characterized by a conserved 200 to 250 amino acid nucleotide-binding and catalytic domain, the AAA+ module. They assemble into hexameric ring complexes that function in the energy-dependent remodeling of macromolecules. Members include ATPASES ASSOCIATED WITH DIVERSE CELLULAR ACTIVITIES.
Preferred term AAA Proteins
Entry term(s) AAA Protein
AAA Superfamily
AAA+ Superfamily
Superfamily, AAA
Superfamily, AAA+
P-Loop NTPases - Related but not broader or narrower
Concept UI M000627063
Preferred term P-Loop NTPases
Entry term(s) NTPases, P-Loop
P Loop NTPases



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