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Descriptor English: Leukocyte Immunoglobulin-like Receptor B1
Descriptor Spanish: Receptor Leucocitario Tipo Inmunoglobulina B1
Descriptor receptor leucocitario tipo inmunoglobulina B1
Entry term(s) LILRB1
antígeno CD85
antígeno CD85J
proteína 2 del transcripto similar a inmunoglobulinas
proteína ILT2
proteína LIR-1
receptor B1 similar a Ig de leucocitos
receptor leucocitario B1 similar a Ig
Scope note: Receptor de los ANTÍGENOS DE HISTOCOMPATIBILIDAD CLASE I (MHC1) que también sirve como receptor de la proteína UL-18, un homólogo de dichos antígenos que se expresa en el CITOMEGALOVIRUS humano. Consta de cuatro dominios C2 de tipo Ig y se expresa principalmente en los linfocitos B y los MONOCITOS, así como en las CÉLULAS DENDRÍTICAS. Su interacción con los MHC1 produce una atenuación de la respuesta inmunitaria.
Descriptor Portuguese: Receptor B1 de Leucócitos Semelhante a Imunoglobulina
Descriptor French: Récepteur B1 de type immunoglobuline des leucocytes
Entry term(s): Antigen, CD85
Antigen, CD85J
CD85 Antigen
CD85J Antigen
ILT2 Protein
Immunoglobulin like Transcript 2 Protein
Immunoglobulin-like Transcript 2 Protein
LILRB1
LIR 1 Protein
LIR-1 Protein
Leukocyte Ig like Receptor B1
Leukocyte Ig-like Receptor B1
Leukocyte Immunoglobulin like Receptor B1
Tree number(s): D12.776.543.750.705.023
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000075362
Scope note: A receptor for HISTOCOMPATIBILITY ANTIGENS CLASS I that also functions as a receptor for the UL18 protein, an MHC class I homolog expressed by human CYTOMEGALOVIRUS. It consists of four Ig-like C2 domains and is expressed primarily by B-cells and MONOCYTES, as well as DENDRITIC CELLS; its interaction with MHC1 functions to down-regulate the immune response.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Antigens, CD (1997-2017)
Receptors, Immunologic (1997-2017)
Public MeSH Note: 2018
History Note: 2018
Related: Immunoglobulin Domains MeSH
DeCS ID: 57138
Unique ID: D000075362
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/05/24
Leukocyte Immunoglobulin-like Receptor B1 - Preferred
Concept UI M000630237
Scope note A receptor for HISTOCOMPATIBILITY ANTIGENS CLASS I that also functions as a receptor for the UL18 protein, an MHC class I homolog expressed by human CYTOMEGALOVIRUS. It consists of four Ig-like C2 domains and is expressed primarily by B-cells and MONOCYTES, as well as DENDRITIC CELLS; its interaction with MHC1 functions to down-regulate the immune response.
Preferred term Leukocyte Immunoglobulin-like Receptor B1
Entry term(s) Antigen, CD85
Antigen, CD85J
CD85 Antigen
CD85J Antigen
ILT2 Protein
Immunoglobulin like Transcript 2 Protein
Immunoglobulin-like Transcript 2 Protein
LILRB1
LIR 1 Protein
LIR-1 Protein
Leukocyte Ig like Receptor B1
Leukocyte Ig-like Receptor B1
Leukocyte Immunoglobulin like Receptor B1



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