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Descriptor English: Triggering Receptor Expressed on Myeloid Cells-1
Descriptor Spanish: Receptor Activador Expresado en Células Mieloides 1
Descriptor receptor activador expresado en células mieloides 1
Entry term(s) Proteína TREM-1
antígeno CD354
receptor desencadenante expresado en células mieloides-1
Scope note: Glucoproteína de membrana de aproximadamente 230 aminoácidos caracterizada por un DOMINIO V DE IG en su mitad N-terminal. Se expresa en los MONOCITOS y los NEUTRÓFILOS en respuesta a la INFLAMACIÓN relacionada con infecciones bacterianas y fúngicas. Desencadena la liberación de QUIMIOCINAS proinflamatorias, CITOCINAS y la expresión de marcadores de activación celular y es un regulador esencial del CHOQUE SÉPTICO.
Descriptor Portuguese: Receptor Gatilho 1 Expresso em Células Mieloides
Descriptor French: Récepteur de déclenchement de type-1 exprimé sur les cellules myéloïdes
Entry term(s): Antigen, CD354
CD354 Antigen
TREM 1 Protein
TREM-1 Protein
Triggering Receptor Expressed on Myeloid Cells 1
Tree number(s): D12.776.395.550.919
D12.776.543.550.919
D12.776.543.750.705.985
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000073871
Scope note: An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Membrane Glycoproteins (2000-2017)
Receptors, Immunologic (2000-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57129
Unique ID: D000073871
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/04/03
Triggering Receptor Expressed on Myeloid Cells-1 - Preferred
Concept UI M000624135
Scope note An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.
Preferred term Triggering Receptor Expressed on Myeloid Cells-1
Entry term(s) Antigen, CD354
CD354 Antigen
TREM 1 Protein
TREM-1 Protein
Triggering Receptor Expressed on Myeloid Cells 1



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