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Descriptor English: Lymphocyte Activation Gene 3 Protein
Descriptor Spanish: Proteína del Gen 3 de Activación de Linfocitos
Descriptor proteína del gen 3 de activación linfocitaria
Entry term(s) antígeno CD223
antígenos CD223
proteínas del gen 3 de activación linfocitaria
Scope note: Proteína relacionada con CD4 con alta afinidad de unión a las moléculas del complejo principal de histocompatibilidad de clase II de la superficie celular. Participa en la disminución de la proliferación de linfocitos T después de la unión a moléculas del complejo principal de histocompatibilidad de clase II.
Descriptor Portuguese: Proteína do Gene 3 de Ativação de Linfócitos
Descriptor French: Protéine LAG-3
Entry term(s): Antigens, CD223
CD223 Antigen
CD223 Antigens
Lymphocyte Activation Gene 3 Proteins
Tree number(s): D12.776.465.806
D12.776.543.750.705.012
D12.776.543.750.705.222.844
D23.050.301.264.894.121
D23.101.100.894.121
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000093322
Scope note: A CD4-related protein with high affinity cell surface binding to MHC class II. It functions in downregulation of T cell proliferation following binding to MHC class II molecules.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Lymphocyte Activation (1998-2022)
Public MeSH Note: 2023; LYMPHOCYTE ACTIVATION GENE 3 PROTEIN was indexed under ANTIGENS, CD 1993-2022
History Note: 2023 (1992)
Related: Lymphocyte Activation MeSH
DeCS ID: 60173
Unique ID: D000093322
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2023/01/01
Date of Entry: 2022/07/14
Revision Date: 2022/07/14
Lymphocyte Activation Gene 3 Protein - Preferred
Concept UI M000753735
Scope note A CD4-related protein with high affinity cell surface binding to MHC class II. It functions in downregulation of T cell proliferation following binding to MHC class II molecules.
Preferred term Lymphocyte Activation Gene 3 Protein
Entry term(s) Antigens, CD223
CD223 Antigen
CD223 Antigens
Lymphocyte Activation Gene 3 Proteins



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