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Descriptor English: Costimulatory and Inhibitory T-Cell Receptors
Descriptor Spanish: Receptores Coestimuladores e Inhibidores de Linfocitos T
Descriptor receptores inhibidores y coestimuladores de células T
Entry term(s) receptores de células T inhibidores y coestimuladores
receptores de linfocitos T coestimuladores e inhibidores
Scope note: Familia de receptores que modulan la activación de los LINFOCITOS T mediante el RECEPTOR DE ANTÍGENOS DE CÉLULAS T. Los receptores son sensibles a uno o más ANTÍGENOS B7 encontrados en la CÉLULAS PRESENTADORAS DE ANTÍGENOS y, dependiendo de la combinación del receptor de ligando específico, modulan una variedad de funciones de las células T tales como las tasas de expansión clonal, SUPERVIVENCIA CELULAR y producción de citoquinas. Aunque comúnmente conocido como receptores coestimuladores, algunos de los receptores tienen efectos inhibitorios como la inducción de TOLERANCIA PERIFÉRICA.
Descriptor Portuguese: Receptores Coestimuladores e Inibidores de Linfócitos T
Descriptor French: Récepteurs costimulateurs et inhibiteurs des cellules T
Entry term(s): Costimulatory T Cell Receptors
Costimulatory T Lymphocyte Receptors
Costimulatory T-Cell Receptors
Costimulatory T-Lymphocyte Receptors
Costimulatory and Inhibitory T Cell Receptors
Costimulatory and Inhibitory T Lymphocyte Receptors
Costimulatory and Inhibitory T-Lymphocyte Receptors
Inhibitory T Cell Receptors
Inhibitory T Lymphocyte Receptors
Inhibitory T-Cell Receptors
Inhibitory T-Lymphocyte Receptors
Receptors, Costimulatory T-Cell
Receptors, Costimulatory T-Lymphocyte
Receptors, Costimulatory and Inhibitory, T-Lymphocyte
Receptors, Costimulatory, T-Lymphocyte
Receptors, Inhibitory T-Cell
Receptors, Inhibitory T-Lymphocyte
Receptors, Inhibitory, T-Cell
T-Cell Receptors, Costimulatory
T-Cell Receptors, Inhibitory
T-Lymphocyte Receptors, Costimulatory
T-Lymphocyte Receptors, Inhibitory
Tree number(s): D12.776.543.750.705.222
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D061025
Scope note: A family of receptors that modulate the activation of T-LYMPHOCYTES by the T-CELL ANTIGEN RECEPTOR. The receptors are responsive to one or more B7 ANTIGENS found on ANTIGEN-PRESENTING CELLS and, depending upon the specific ligand-receptor combination, modulate a variety of T-cell functions such as the rate of clonal expansion, CELL SURVIVAL and cytokine production. Although commonly referred to as costimulatory receptors, some of the receptors have inhibitory effects such as inducing PERIPHERAL TOLERANCE.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Public MeSH Note: 2012
History Note: 2012
DeCS ID: 54633
Unique ID: D061025
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2012/01/01
Date of Entry: 2011/06/24
Costimulatory and Inhibitory T-Cell Receptors - Preferred
Concept UI M0556118
Scope note A family of receptors that modulate the activation of T-LYMPHOCYTES by the T-CELL ANTIGEN RECEPTOR. The receptors are responsive to one or more B7 ANTIGENS found on ANTIGEN-PRESENTING CELLS and, depending upon the specific ligand-receptor combination, modulate a variety of T-cell functions such as the rate of clonal expansion, CELL SURVIVAL and cytokine production. Although commonly referred to as costimulatory receptors, some of the receptors have inhibitory effects such as inducing PERIPHERAL TOLERANCE.
Preferred term Costimulatory and Inhibitory T-Cell Receptors
Entry term(s) Costimulatory and Inhibitory T Cell Receptors
Costimulatory and Inhibitory T Lymphocyte Receptors
Costimulatory and Inhibitory T-Lymphocyte Receptors
Receptors, Costimulatory and Inhibitory, T-Lymphocyte
Costimulatory T-Cell Receptors - Narrower
Concept UI M0556119
Preferred term Costimulatory T-Cell Receptors
Entry term(s) Costimulatory T Cell Receptors
Costimulatory T Lymphocyte Receptors
Costimulatory T-Lymphocyte Receptors
Receptors, Costimulatory T-Cell
Receptors, Costimulatory T-Lymphocyte
Receptors, Costimulatory, T-Lymphocyte
T-Cell Receptors, Costimulatory
T-Lymphocyte Receptors, Costimulatory
Inhibitory T-Cell Receptors - Narrower
Concept UI M0556120
Preferred term Inhibitory T-Cell Receptors
Entry term(s) Inhibitory T Cell Receptors
Inhibitory T Lymphocyte Receptors
Inhibitory T-Lymphocyte Receptors
Receptors, Inhibitory T-Cell
Receptors, Inhibitory T-Lymphocyte
Receptors, Inhibitory, T-Cell
T-Cell Receptors, Inhibitory
T-Lymphocyte Receptors, Inhibitory



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