| Descriptor English: | Agammaglobulinaemia Tyrosine Kinase | ||||||
| Descriptor Spanish: |
Agammaglobulinemia Tirosina Quinasa
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| Descriptor Portuguese: | Tirosina Quinase da Agamaglobulinemia | ||||||
| Descriptor French: | Agammaglobulinaemia tyrosine kinase | ||||||
| Entry term(s): |
B Cell Progenitor Kinase Bruton Tyrosine Kinase Bruton's Tyrosine Kinase Brutons Tyrosine Kinase Kinase, Agammaglobulinaemia Tyrosine Kinase, Bruton's Tyrosine Tyrosine Kinase, Agammaglobulinaemia Tyrosine Kinase, Bruton's |
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| Tree number(s): |
D08.811.913.696.620.682.725.025 D12.776.476.568.025 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000077329 | ||||||
| Scope note: | A non-receptor tyrosine kinase that is essential for the development, maturation, and signaling of B-LYMPHOCYTES. It contains an N-terminal zinc finger motif and localizes primarily to the PLASMA MEMBRANE and nucleus of B-lymphocytes. Mutations in the gene that encode this kinase are associated with X-LINKED AGAMMAGLOBULINEMIA. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.10.2 | ||||||
| Public MeSH Note: | 2019; AGAMMAGLOBULINAEMIA TYROSINE KINASE was indexed under PROTEIN-TYROSINE KINASES 1993-2018 |
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| History Note: | 2019 (1993) |
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| DeCS ID: | 57613 | ||||||
| Unique ID: | D000077329 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2019/01/01 | ||||||
| Date of Entry: | 2018/07/09 | ||||||
| Revision Date: | 2018/06/19 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Agammaglobulinaemia Tyrosine Kinase
- Preferred
| Concept UI |
M0219038 |
| Scope note | A non-receptor tyrosine kinase that is essential for the development, maturation, and signaling of B-LYMPHOCYTES. It contains an N-terminal zinc finger motif and localizes primarily to the PLASMA MEMBRANE and nucleus of B-lymphocytes. Mutations in the gene that encode this kinase are associated with X-LINKED AGAMMAGLOBULINEMIA. |
| Preferred term | Agammaglobulinaemia Tyrosine Kinase |
| Entry term(s) |
B Cell Progenitor Kinase Bruton Tyrosine Kinase Bruton's Tyrosine Kinase Brutons Tyrosine Kinase Kinase, Agammaglobulinaemia Tyrosine Kinase, Bruton's Tyrosine Tyrosine Kinase, Agammaglobulinaemia Tyrosine Kinase, Bruton's |
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