DeCS

Descriptor English:

Palonosetron

Descriptor Spanish:

Palonosetrón

Spanish from Spain

Descriptor	palonosetrón
Entry term(s)	(3R)-palonosetrón 2-(1-azabiciclo(2.2.2)oct-3-il)-2,3,3a,4,5,6-hexahidro-1H-benzo(de)isoquinolina-1-ona 2-QHBIQO RS 25233 197 RS 25233 198 RS 25233-197 RS 25233-198 RS 25233197 RS 25233198 RS 25259 RS 25259 197 RS 25259 198 RS 25259-197 RS 25259-198 RS 25259197 RS 25259198 RS-25233-197 RS-25233-198 RS-25259 RS-25259-197 RS-25259-198 RS25233197 RS25233198 RS25259 RS25259197 RS25259198 aloxi hidrocloruro de palonosetrón isómero (R-(R,R)) del palonosetrón isómero (R-(R,S)) del palonosetrón isómero (S-(R,S)) del palonosetrón
Scope note:	Derivado isoquinolínico y quinuclidínico que actúa como antagonista de los RECEPTORES DE SEROTONINA 5-HT3. Se usa en la prevención de las náuseas y vómitos inducidos por la quimioterapia citotóxica y para la prevención de las náuseas y vómitos posoperatorios.

Descriptor Portuguese:

Palonossetrom

Descriptor French:

Palonosétron

Entry term(s):

Chlorhydrate de palonosétron
RS-25233-197
RS-25233-198
RS-25259
RS-25259-197
RS-25259-198

Tree number(s):

D03.605.687.319
D03.633.100.531.629

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000077924

Scope note:

Isoquinoline and quinuclidine derivative that acts as a 5-HT3 RECEPTOR antagonist. It is used in the prevention of nausea and vomiting induced by cytotoxic chemotherapy, and for the prevention of post-operative nausea and vomiting.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Antiemetics
Serotonin 5-HT3 Receptor Antagonists

Registry Number:

5D06587D6R

CAS Type 1 Name:

1H-Benz(de)isoquinolin-1-one, 2-((3S)-1-azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-, (3aS)-

DeCS ID:

57774

Unique ID:

D000077924

Documents indexed in the Virtual Health Library (VHL):

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