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Descriptor in English: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
Descriptor in Spanish: 1-(5-Isoquinolinesulfonil)-2-Metilpiperazina
Descriptor in Portuguese: 1-(5-Isoquinolinasulfonil)-2-Metilpiperazina
Descriptor in French: 5-(2-Méthyl-pipérazine-1-sulfonyl)isoquinoléine
Entry term(s): 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine
H 7
H-7
Tree number(s): D02.886.590.700.545
D03.383.606.527
D03.633.100.531.400
Scope note: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Online Note: use 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE (NM) to search 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE 1985-96
History Note: 97; was 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE (NM) 1985-96
DeCS UI: 32992
Descriptor UI: D019307
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2017/04/10
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - Preferred
Concept UI M0028749
Scope note A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
Preferred term 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
Entry term(s) 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine
H 7
H-7



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