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Descriptor English: Cytochrome P-450 CYP2J2
Descriptor Spanish: Citocromo P-450 CYP2J2
Descriptor CYP2J2 del citocromo P450
Entry term(s) CYP2J2
araquidonato-epoxigenasa
araquidonato-oxigenasa del citocromo P-450
epoxigenasa del citocromo P-450
epoxigenasa del ácido araquidónico
epoxigenasa del ácido araquidónico dependiente de NADPH
Scope note: Enzima del citocromo P450 que interviene en la oxidación de ÁCIDOS GRASOS POLIINSATURADOS (AGPI) en epóxidos de AGPI que funcionan como potentes mediadores lipídicos. Esta enzima, codificada por el gen CYP2J2, metaboliza el ÁCIDO ARAQUIDÓNICO en ácidos epoxieicosatrienoicos (EET) que producen efectos biológicos tales como VASODILATACIÓN.
Descriptor Portuguese: Citocromo P-450 CYP2J2
Descriptor French: CYP2J2 du cytochrome P450
Entry term(s): Acid Epoxygenase, Arachidonic
Arachidonate Epoxygenase
Arachidonic Acid Epoxygenase
CYP2J2
Cytochrome P 450 Arachidonate Oxygenase
Cytochrome P 450 CYP2J2
Cytochrome P-450 Arachidonate Oxygenase
Cytochrome P-450 Epoxygenase
Epoxygenase, Arachidonate
Epoxygenase, Arachidonic Acid
NADPH Dependent Arachidonic Acid Epoxygenase
NADPH-Dependent Arachidonic Acid Epoxygenase
Tree number(s): D08.244.453.003
D08.811.682.690.708.170.005
D10.251.355.128
D12.776.422.220.453.005
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000090762
Scope note: A cytochrome P450 enzyme involved in oxidizing POLYUNSATURATED FATTY ACIDS (PUFA) to PUFA epoxides which function as potent lipid mediators. This enzyme, encoded by CYP2J2 gene, metabolizes ARACHIDONIC ACID to epoxyeicosatrienoic acids (EETs) which produce biological effects including VASODILATION.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.14.14.1
Public MeSH Note: 2022; ARACHIDONATE EPOXYGENASE was indexed under CYTOCHROME P-450 ENZYME SYSTEM 1987-2021, and under OXYGENASES 1985-2008
History Note: 2022 (1985)
DeCS ID: 59818
Unique ID: D000090762
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/06/28
Cytochrome P-450 CYP2J2 - Preferred
Concept UI M0590245
Scope note A cytochrome P450 enzyme involved in oxidizing POLYUNSATURATED FATTY ACIDS (PUFA) to PUFA epoxides which function as potent lipid mediators. This enzyme, encoded by CYP2J2 gene, metabolizes ARACHIDONIC ACID to epoxyeicosatrienoic acids (EETs) which produce biological effects including VASODILATION.
Preferred term Cytochrome P-450 CYP2J2
Entry term(s) CYP2J2
Cytochrome P 450 CYP2J2
Arachidonate Epoxygenase - Broader
Concept UI M0434929
Preferred term Arachidonate Epoxygenase
Entry term(s) Acid Epoxygenase, Arachidonic
Arachidonic Acid Epoxygenase
Cytochrome P 450 Arachidonate Oxygenase
Cytochrome P-450 Arachidonate Oxygenase
Cytochrome P-450 Epoxygenase
Epoxygenase, Arachidonate
Epoxygenase, Arachidonic Acid
NADPH Dependent Arachidonic Acid Epoxygenase
NADPH-Dependent Arachidonic Acid Epoxygenase



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