Search
Descriptor in English: Aryl Hydrocarbon Hydroxylases
Descriptor in Spanish: Hidrocarburo de Aril Hidroxilasas
Descriptor in Portuguese: Hidrocarboneto de Aril Hidroxilases
Descriptor in French: Aryl hydrocarbon hydroxylases
Entry term(s): Hydroxylases, Aryl Hydrocarbon
Microsomal Monooxygenases
Monooxygenases, Microsomal
Monooxygenases, Xenobiotic
Xenobiotic Monooxygenases
Tree number(s): D08.244.453.005
D08.811.682.690.708.170.010
D12.776.422.220.453.010
Scope note: A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 75
DeCS UI: 23163
Descriptor UI: D001189
Date Established: 1975/09/01
Date of Entry: 1974/11/11
Revision Date: 2016/05/27
Aryl Hydrocarbon Hydroxylases - Preferred
Concept UI M0001774
Scope note A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.
Preferred term Aryl Hydrocarbon Hydroxylases
Entry term(s) Hydroxylases, Aryl Hydrocarbon
Microsomal Monooxygenases
Monooxygenases, Microsomal
Xenobiotic Monooxygenases - Narrower
Concept UI M0417290
Scope note Monooxygenases that oxidize exogenous substrates.
Preferred term Xenobiotic Monooxygenases
Entry term(s) Monooxygenases, Xenobiotic



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.


Go to survey