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Descriptor English: Methimazole
Descriptor Spanish: Metimazol
Descriptor metimazol
Entry term(s) tiamazol
Scope note: Tioureileno, agente antitiroideo que inhibe la formación de hormonas tiroideas al interferir en la incorporación de iodo en los residuos tirosilo de la tiroglobulina. Esto se realiza interfiriendo con la oxidación del ión ioduro y grupos iodotirosilos mediante la inhibición de la enzima peroxidasa.
Descriptor Portuguese: Metimazol
Descriptor French: Thiamazol
Entry term(s): Thiamazole
Tree number(s): D02.886.489.600
D03.383.129.308.535
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008713
Scope note: A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antithyroid Agents
Registry Number: 554Z48XN5E
CAS Type 1 Name: 2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-
DeCS ID: 8890
Unique ID: D008713
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Thiamazol - Preferred
Concept UI M0013573
Preferred term Thiamazol
Entry term(s) Thiamazole



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