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Descriptor English: Metyrapone
Descriptor Spanish: Metirapona
Descriptor Portuguese: Metirapona
Descriptor French: Métyrapone
Entry term(s): Methbipyranone
Methopyrapone
Metopiron
Metopirone
Métopirone
SU 4885
Tree number(s): D03.383.725.463
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008797
Scope note: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites
Enzyme Inhibitors
Registry Number: ZS9KD92H6V
CAS Type 1 Name: 1-Propanone, 2-methyl-1,2-di-3-pyridinyl-
Public MeSH Note: 66
History Note: 66(64)
DeCS ID: 8971
Unique ID: D008797
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Metyrapone - Preferred
Concept UI M0013712
Scope note An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
Preferred term Metyrapone
Entry term(s) Methbipyranone
Methopyrapone
SU 4885 - Narrower
Concept UI M0373555
Preferred term SU 4885
Metopirone - Narrower
Concept UI M0013713
Preferred term Metopirone
Entry term(s) Metopiron
Métopirone



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