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Descriptor English: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Descriptor Spanish: 1-Metil-4-fenil-1,2,3,6-Tetrahidropiridina
Descriptor Portuguese: 1-Metil-4-Fenil-1,2,3,6-Tetra-Hidropiridina
Descriptor French: 1-Méthyl-4-phényl-1,2,3,6-tétrahydropyridine
Entry term(s): MPTP
N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Tree number(s): D03.383.725.450
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015632
Scope note: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
RE radiation effects
SD supply & distribution
ST standards
TU therapeutic use
UR urine
Entry Combination: poisoning:MPTP Poisoning
toxicity:MPTP Poisoning
Pharm Action: Neurotoxins
Dopamine Agents
Registry Number: 9P21XSP91P
CAS Type 1 Name: Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-phenyl-
Previous Indexing: Pyridines (1966-1989)
Public MeSH Note: 90
History Note: 90
DeCS ID: 24779
Unique ID: D015632
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2016/05/27
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - Preferred
Concept UI M0023971
Scope note A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
Preferred term 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Entry term(s) MPTP
N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine



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