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Descriptor English: Nicotine
Descriptor Spanish: Nicotina
Descriptor nicotina
Scope note: La nicotina es un alcaloide altamente tóxico. Es el agonista prototípico de los receptores nicotínicos colinérgicos, actuando estimulando intensamente las neuronas y, finalmente, bloqueando la transmisión sináptica. La nicotina también es importante desde el punto de vista médico debido a su presencia en el humo del tabaco.
Descriptor Portuguese: Nicotina
Descriptor French: Nicotine
Entry term(s): Nicotine Bitartrate
Nicotine Tartrate
Tree number(s): D03.132.760.570
D03.383.725.518
SP4.606.806.945.200.606.581
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009538
Scope note: Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Smoking Cessation Agents
Ganglionic Stimulants
Nicotinic Agonists
Registry Number: 6M3C89ZY6R
CAS Type 1 Name: Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-
DeCS ID: 9723
Unique ID: D009538
NLM Classification: QV 137
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/04/10
Nicotine - Preferred
Concept UI M0014836
Scope note Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Preferred term Nicotine
Nicotine Bitartrate - Narrower
Concept UI M0014837
Preferred term Nicotine Bitartrate
Entry term(s) Nicotine Tartrate



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