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Descriptor English: Torsemide
Descriptor Spanish: Torasemida
Descriptor Portuguese: Torasemida
Descriptor French: Torasémide
Entry term(s): 1-Isopropyl-3-((4-(3-methylphenylamino)pyridine)-3-sulfonyl)urea
1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea
Demadex
Torasemide
Tree number(s): D02.065.884.891
D02.886.590.700.891
D03.383.725.905
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077786
Scope note: A pyridine and sulfonamide derivative that acts as a sodium-potassium chloride symporter inhibitor (loop diuretic). It is used for the treatment of EDEMA associated with CONGESTIVE HEART FAILURE; CHRONIC RENAL INSUFFICIENCY; and LIVER DISEASES. It is also used for the management of HYPERTENSION.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antihypertensive Agents
Diuretics
Sodium Potassium Chloride Symporter Inhibitors
Registry Number: W31X2H97FB
CAS Type 1 Name: 3-Pyridinesulfonamide, N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-
Public MeSH Note: 2019; TORSEMIDE was indexed under SULFONAMIDES 1980-2018
History Note: 2019 (1980)
DeCS ID: 57759
Unique ID: D000077786
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/05/21
Torsemide - Preferred
Concept UI M0086132
Scope note A pyridine and sulfonamide derivative that acts as a sodium-potassium chloride symporter inhibitor (loop diuretic). It is used for the treatment of EDEMA associated with CONGESTIVE HEART FAILURE; CHRONIC RENAL INSUFFICIENCY; and LIVER DISEASES. It is also used for the management of HYPERTENSION.
Preferred term Torsemide
Entry term(s) Torasemide
1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea - Related but not broader or narrower
Concept UI M000641952
Preferred term 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea
Entry term(s) 1-Isopropyl-3-((4-(3-methylphenylamino)pyridine)-3-sulfonyl)urea
Demadex - Narrower
Concept UI M0086130
Preferred term Demadex



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