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Descriptor English: Antibody Affinity
Descriptor Spanish: Afinidad de Anticuerpos
Descriptor afinidad del anticuerpo
Entry term(s) afinidad de los anticuerpos
avidez de los anticuerpos
Scope note: Medida de la fuerza de unión entre un anticuerpo y un hapteno o determinante antigénico simple. Depende de la proximidad del ajuste estereoquímico entre los sitios de combinación estereoquímica y los determinantes antigénicos, del tamaño de la superficie de contacto entre ellos y de la distribución de los grupos cargados e hidrofóbicos. Incluye el concepto de "avidez", que hace referencia a la fuerza de la unión antígeno-anticuerpo después de la formación de complejos reversibles.
Descriptor Portuguese: Afinidade de Anticorpos
Descriptor French: Affinité des anticorps
Entry term(s): Affinité d'anticorps
Avidité des anticorps
Tree number(s): G12.040
G12.122.125
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000915
Scope note: A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.
Annotation: do not confuse with BINDING SITES, ANTIBODY or ANTIGENIC DETERMINANTS
Allowable Qualifiers: DE effets des médicaments et des substances chimiques
ES éthique
GE génétique
IM immunologie
PH physiologie
RE effets des radiations
DeCS ID: 923
Unique ID: D000915
NLM Classification: QW 570
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1979/01/01
Date of Entry: 1977/12/02
Revision Date: 2016/06/02
Affinité des anticorps - Preferred
Concept UI M0001362
Preferred term Affinité des anticorps
Entry term(s) Affinité d'anticorps
Avidité des anticorps - Narrower
Concept UI M0001363
Preferred term Avidité des anticorps



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